Ubiquitin

NEOPLASIA Presented by Dr Abudu Emmanuel Kunle (MBBS, M.Sc, FMCPath) Senior Lecturer and Consultant Histopathologist University of Uyo Teaching Hospital,Uyo, Akwa- Ibom State, Nigeria. Neoplasia means the process of new growth whilst Neoplasm means a new growth. Sometimes, the parenchyma cells stimulate the formation of an abundant collagenous stroma, referred to as desmoplasia. Some tumours e.g. some cancers of breast are stony hard or scirrhous. Sarcomas have little connective tissue stroma and

Cardiovascular disease (CVD) is a global pandemic. Whereas CVD was once a relatively minor disease, it has matured into the killer responsible for 30% of global deaths each year1. Although its prevalence is high and its manifestation assumes the forms of numerous diseases, many of those who suffer from CVD share a commonality: high blood pressure2. By increasing the chances of stroke, congestive heart disease, and heart failure, hypertension is a major risk factor of CVD. As of the year 2000, one

Chapter 1: Introduction 1.1 RNA interference regulates gene expression in eukaryotes The flow of genetic information within a living organism was first stated by Crick as “DNA makes RNA and RNA makes protein” (Crick 1956). In response to environmental stimuli, the dynamic modulation of specific gene products (mRNAs and proteins) confers flexibility and adaptability to prokaryotes, eukaryotes, and viruses (Crick 1956). Proper gene regulation is essential for cell growth, development, proliferation

Paget’s disease of the bone (PDB), also called Osteitis Deformans, is a chronic, slowly progressive skeletal condition of abnormally rapid bone destruction and reformation. PDB is the second most common bone remodeling disease after osteoporosis. The new bone is structurally abnormal, dense and fragile. The bones that are frequently affected are in the spine, skull, pelvis and lower legs. The disease does not spread bone to bone, it will stay constant in the affected bone or bones throughout

Parkinson 's disease Twanda H. Lewis North Carolina Wesleyan Dr. Quinan Parkinson 's Disease Twanda H. Lewis North Carolina Wesleyan Dr. Quinan Outline Abstract………………………………………………………………………………………5 Introduction………………………………………………………………………………. 6 Symptoms…………………………………………………………………………………. 6 Tremor…………………………………………………………………………………….… 6 Slow Movement………………………………………………………………………… 6 Rigid Muscles…………………………………………………………………………….. 7 Disfigured Posture…………………………………………………………………….. 7 Loss of

In October of 1991, the United States Congress passed a law dedicating $2 million to fund an office of the National Institute of Health dedicated to the investigation of nontraditional medical practices. Seven years later, the National Center for Complementary and Alternative Medicine (NCCAM) became an official branch of the National Institutes of Health. Although alternative medicine has only recently gained official recognition in the United States, the mind/body practices that pervade NCCAM’s

Introduction 1. Normal mammary gland 1.1 normal mammary gland anatomies The normal breast sits on the chest muscle, consisting mainly of adipose tissue, also known as mammary fat pad. The mature mammary gland is composed of 15-20 lobes, which are each composed of smaller structure called lobules. Tiny Lactiferous ducts connect lobules to each other. (Fig. 1b) (Schneider and Bocker). A typical structure of duct is composed of a hollow lumen, enclosed by a layer of epithelial luminal cells that produce

Case Study 15 Scenario J.F. is a 50-year-old married homemaker with a genetic autoimmune defi ciency; she has suffered from recurrent bacterial endocarditis. The most recent episodes were a Staphylococcus aureus infection of the mitral valve 16 months ago and a Streptococcus mutans infection of the aortic valve 1 month ago. During this latter hospitalization, an ECG showed moderate aortic stenosis, moderate aortic insuffi - ciency, chronic valvular vegetations, and moderate left atrial enlargement

Name: _Leroy Johnson __________________________________ Date: ______________Comprehensive Study Guide. Test will only be Multiple choice 1. The feature that most clearly separates eukaryotes from prokaryotes is the presence of _______ in eukaryotic cells. A) ribosomes B) oxidative phosphorylation C) DNA molecules -D) a nucleus 2. Cytoplasmic organelles are - A) absent in prokaryotic cells; present in eukaryotic cells. B) present in both prokaryotic and eukaryotic cells