Route availability

Transmucosal route of drug delivery is widely accepted as a suitable way for administration of drugs via buccal mucosa for local and systemic applications. Compared to other transmucosal routes, buccal mucosa is approximately an immobile, highly accessible mucosa that characterized by wide area of smooth muscles1. Moreover, buccal drug delivery systems offer various advantages including the direct entry to the systemic circulation through the internal jugular vein avoiding first pass metabolism and

8. SUMMERY AND CONCLUTION Topical route is the most commonly used route for drug administration through different route of administration are used for the delivery of drugs, topical route remain the preferred mode. NLC are lipid nanoparticles. They offer a great potential to reduce the side effect of drug and increase the therapeutic effectiveness as topical drug delivery system. Ketoconazole is an imidazole derivative with broad spectrum antifungal activity. Ketoconazole interacts with 14 α-dimethylase

Throughout the first few weeks of working on the Mental Heath Unit at Victoria Hospital, I was exposed to many new and different situations in regards to patient care. One situation in particular that stuck out to me occurred during my first week when I was working with a patient who had schizophrenia and paranoia. During this time, I was required to give this gentleman his intramuscular (IM) depot injection of Invega Sustenna, which assists in managing the symptoms of schizophrenia. For confidentiality

AR/LR : Analytical reagent/Laboratory reagent CDR : Cumulative drug release FTIR : Fourier Transform Infrared spectroscopy ICH : International Conference for Harmonization Mg : Milligram ODT : Orally disintegrating

Midterm Review 1.1 Big Geography and the Peopling of the Earth 1. Archeologists believe that the decisive differentiation between humans and apes occurred from 6 to 8 million years ago. 2. They have interpreted to different DNA analysis of bone fragments to show bipedalism. From the creature Ardepithecus ramidus, many different species of humans have developed from there. 3. Humans first appear on Earth in the Paleolithic Age where they inhabited all continents except for Antarctica. Homo sapiens

will be loaded in trains and trucks from the Iraqi Grand port of Al-Faw Southern of the country, and then will travel across the country to Turkey and then to Europe. This would give shippers companies an alternative to traditional but no longer route around the Arabian Peninsula, up through the Suez Canal of Egypt. Iraq is a very rich country and has a lot of potential and

A study by Hariharan M, Wheatley TA, and Price JC (1997) investigated controlled release on two kinds of carrageenan, lambda carrageenan (Viscarin GP-209) and iota-carrageenan (Gelcarin GP-379). They analyzed their respective compression capabilities through the use of a Strokes single punch machine. Yield pressure was calculated at 81.3 Pa for iota carrageenan and 105.2 MPa for lambda-carrageenan through the use of Heckel plots out of die tablet densities. The results proved linear. Both carrageenan

free of clots, used appropriate medications and protected from bloodstream infections. Question 4 First step is to identify the patient, explain the procedure and ask about any allergies. Name of the medication, amount (dose) of medication, route of administration, time to be administered. Select the medication and check the medication label three times to ensure that the

Three honks. Ready, set, go. The moment every car enthusiast dreams of at night. Chances are you might not even know what a car enthusiast is. Some say it's your average car guy that likes to stare at cars and talk about cars all day long, but there's much more too it. See, you can't be the average person to be a car enthusiast. The average person may see an old car at a junkyard and just think well, it's just another piece of junk. Too a car enthusiast he sees a piece of art. He or she witnesses

administration such as avoiding the first pass effect and bypass the gastrointestinal tract and solve the decreased in the residence time which mostly result in less absorption and less effective dose. Not only the oral route but even comparing the new system with parenteral route it shows a rapid onset of action as the drugs delivered directly to the systemic circulation. The lipophilicity of the drugs and the permeability of the nasal mucosa