Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 9, Problem 42SA
Summary Introduction

To review:

The deficiency of pyruvate carboxylase thatresults in lactic aciduria, an illness where lactate appears in the urine.

Introduction:

In all aerobic living organisms, the citric acid cycle or Kreb’s cycle is present in order to release the energy stored in a 2-carbon acetyl, that is, acetyl-CoA (Coenzyme A) by a series of biochemical reactions. This cycle occurs in the matrix region of mitochondria in a living cell. Acetyl-CoA is formed from the pyruvate in the process of glycolysis and in the catabolism of fatty acids.

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