CAMPBEL BIOLOGY:CONCEPTS & CONNECTIONS
CAMPBEL BIOLOGY:CONCEPTS & CONNECTIONS
10th Edition
ISBN: 9780136538820
Author: Taylor
Publisher: INTER PEAR
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Chapter 9, Problem 10TYK

A series of matings shows that the recombination frequency between the black-body gene (problem 9) and the gene for dumpy (shortened) wings is 36%. The recombination frequency between purple eyes and dumpy wings is 41%. What is the sequence of these three genes on the chromosome?

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Assume you are mapping genes A, B, C, and D in Drosophila. You know that these genes are linked on the same chromosome, and you determine the recombination frequencies between each pair of genes to be as follows: A–B, 8%; A– C, 28%; A–D, 25%; B–C, 20%; B–D, 33%. (a) Describe how you determined the recombination frequency for each pair of genes. (b) Draw a chromosome map based on your data.
In an electrophoretic gel across which is applied a powerful electrical alternating pulsed field, the DNA of the haploid fungus Neurospora crassa (n = 7) moves slowly but eventually forms seven bands, which represent DNA fractions that are of different sizes and hence have moved at different speeds. These bands are presumed to be the seven chromosomes. How would you show which band corresponds to which chromosome?
L, R, P and D are four genes located on the same chromosome in a diploid organism. Map distances between different pairs of genes were determined and the following results obtained. Based on these data, what is the order of the genes on the chromosome? D-R: 35 CM P-D: 5 CM L-R: 10 CM D-P: 30 CM D-L 25 CM P-R: 40 CM Note that only one orientation of the order is given as an answer choice. For example: ABCD has the same order as DCBA, but only ABCD would be listed as a possible answer. So be sure to check both orientations when comparing your gene order to the possible answer choices. D-L-P-R P-D-L-R P-R-D-L L-P-R-D R-L-D-P
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