EBK BROCK BIOLOGY OF MICROORGANISMS
EBK BROCK BIOLOGY OF MICROORGANISMS
15th Edition
ISBN: 8220103633352
Author: Stahl
Publisher: PEARSON
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Chapter 7.11, Problem 2MQ
  • What prevents the toxin component of TA modules from killing the cell under normal conditions?
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1. NSF is an enzyme that uses the energy of ATP hydrolysis to disassemble complexes between v-SNAREs and t-SNAREs.a) Why do you suppose such an enzyme is needed?b) If NSF were suddenly inactivated and then the cells were examined a short time later, what types of effects would you expect to see?
Poliovirus is highly cytopathic both in cultured cells and in animals. Inoculation of mice with poliovirus leads to a robust antibody and cellular response. Explain why mice infected with a poliovirus mutant that cannot cause cell death have poor antibody and cellular responses. What would be one strategy to restore robust antibody and cellular responses in mice infected with this mutant virus?
Which of the following protein domains would you expect to find in an "easily druggable" target but NOT in an "undruggable" target. An easily druggable target is defined as a target with an easily accessible active site than can be activated or inhibited. Please Explain. Answer Choices: A) Extracellular domain B) Intracellular domain C) Membrane Spanning domain D) ATP-binding domain E) Protein Binding domain

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EBK BROCK BIOLOGY OF MICROORGANISMS

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