Concept explainers
To describe: The number of ATP molecules that would be produced by the oxidation of fatty acid that has 16 carbons.
Introduction: The fatty-acid oxidation (β-oxidation) is a
Explanation of Solution
During the catabolism of fats, one molecule of ATP is used in each round of beta-oxidation and produces one molecule each of NADH and FADH2. Seven rounds of beta-oxidation would convert the fatty acid into eight molecules of acetyl-CoA for a 16-carbon fatty acid. In the Krebs cycle, the oxidation of each acetyl-CoA produced 10 molecules of ATP.
Thus, the overall yield of ATP from 16-carbon fatty acid would be a net gain of 21 ATP from seven rounds of beta-oxidation (gain of 4 ATP per round – 1 per round of prime reaction) + 80 ATP from the oxidation of 8 acetyl-CoA = 101 ATP molecules.
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