Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 7, Problem 19P
Interpretation Introduction
Interpretation:
The reason corresponding to the fact that hydroxyurea can be useful therapy for patients having sickle-cell anemia is to be stated.
Concept introduction:
Proteins are the
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- I need help. Please tell me the correct answers please and thank you .arrow_forwardHelp. There can be more than one right:arrow_forwardHydroxyurea has been shown to increase the expression of fetal hemoglobin in adult red blood cells, by a mechanism that remains unclear. Explain why hydroxyurea can be a useful therapy for patients with sickle-cell anemia.arrow_forward
- Need help with this. Also provided an explanation.arrow_forwardCold-Reacting Autoantibodies. Most adult sera contain low titers of cold-reacting autoantibodies, most notably autoanti-I, autoanti-H, and autoanti-IH. These antibodies are usually IgM and of no clinical significance. They are troublesome in that they may interfere with the detection of significant antibodies, resulting in prolonged workups and delayed transfusions.Cold-reacting autoantibodies may be suspected when the screen cells, panel cells, and the autocontrol areall positive at the immediate spin phase and reactivity gets weaker or disappears with incubation at 37°C (Fig. 9–18).Certain cold autoantibodies activate complement and may be detected at the AHG phase when using complement-containing AHG reagent. These autoanti- bodies may be mistaken for weakly reacting IgG antibodies.Although it is not usually necessary to determine the specificity of the cold autoantibody, testing against additional cells may confirm its presence. Cord blood cells that lack the I antigen are of…arrow_forwardSituational task. The patient has a significant decrease in blood hemoglobin. No blood loss was observed. Diet and normalization of nutrition did not affect the increase in hemoglobin. What could be the cause of this phenomenon?arrow_forward
- Please help me with this question. More than one answer may be correct. THe graph relating to the information is included below. Dilated cardiomyopathy (DCM) is a condition in which the wall of the heart, starting with the left ventricle, stretches and thins. This prevents the heart from pumping effectively and can be life threatening. The above graph shows mRNA expression (left pane) and protein expression (right pane) for three molecular components of cardiomyocytes (GJA3 is the gene that encodes for Connexin 46, DSP is the gene that encodes for Desmoplakin, and CTNNA3 is the gene that encodes for Catenin α-3) between DCM cells and healthy cardiomyocytes (CNT). Based on the above figure, which of the following issues are hearts with dilated cardiomyopathy likely to suffer? Options: impaired electrical conduction between cells impaired cell-cell communication poor cell-cell adhesion decreased energetic output from mitochondria impaired ability to pass mitochondria between cellsarrow_forwardPLEASE DONT CANCEL. ILL UPVOTE WITH ALL OF MY ACCS. Make a drug study study about cetirizine (diphenhydramine hydrochloride) drug and fill up the corresponding details in the table. - The drug study shall be patient-based, and based on the informations provided below. - Nursing responsibilities would be in ADPIE form. MAIN DRUG: cetirizine (diphenhydramine hydrochloride) INFORMATIONS: Cetirizine Age: 18/F Occupation: Basketball player Weight and BMI: 50 KGS/22 Blood pressure: 100/70 Heart rate: 60 Respiratory rate: 15 Temperature: 36.2 Diagnosis: Allergic reaction with eating shrimp with facial angioedema Chief complaint: Swollen ears and mouth Prescription: Cetirizine PO 5 mg ODarrow_forwardNeed help. do explainarrow_forward
- care of them. The best way do to so is to have a healthy lifestyle, which includes proper rest, ehough exercise, proper hygiene, and balanced diet. Also, you must avoid doing harmful things or having unhealthy habits such as smoking, intake of illegal drugs, and alcohol drinking. Eating foods with a lot of salt and fats should also be avoided. If the respiratory and circulatory systems are not properly taken care of, you might get diseases that can be detrimental to your health. Take the Written Assignments A. Write A if the disease mentioned in each item is associated with the respiratory system, and B if it is associated with the circulatory system. You may research to do this activity. Write your answers on the blanks. 1: Bronchitis 2. Stroke 3.' Hemophilia 4. Hypertension 5. Pneumonia 6. Heart failure 7. Arteriosclerosis 8. Asthma 9. Cystic fibrosis 10. Varicose veins DYnamic Minds: A Science Workbook (Grade 9)arrow_forwardsurfactant. She has signs of low oxygen and high carbon dioxide. Explain why the lack of surfactant would result in respiratory distress. Furthermore, what type of acid-base disorder might she develop and how would her body compensate. Be detailed in your explanation and support your answer with facts from your textbook, research, and articles from scholarly journals. In addition, remember to add references in APA format to your posts to avoid plagiarism.arrow_forwardgive correct option. Polyisocyanates are involved in the induction of the full spectrum of hypersensitivity responses and nonimmune inflammatory reactions including asthma. Which of the following statement is not correct with respect to these observations and impact on immunity? a. A person once sensitized to polyisocyanate can demonstrate group reactivity to this set of compounds. b. Individuals having an acute exposure to toluene diisocyanate is more likely to develop hypersensitivity then individuals chronically exposed to low vapor levels. c. A mechanism for this hypersensitivity is the toluene diisocyanate forms a covalent bond with proteins that are part of the airway resulting in the immune system developing a response to “self” proteins. d. Adaptive immunity can interact or “message” the Innate immune system to up or down regulate its expression. e. All of the statements are correct.arrow_forward
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