An Introduction to Statistical Methods and Data Analysis
An Introduction to Statistical Methods and Data Analysis
7th Edition
ISBN: 9781305269477
Author: R. Lyman Ott, Micheal T. Longnecker
Publisher: Cengage Learning
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Chapter 6.9, Problem 28E

The paper “Effect of Long-Term Blood Pressure Control on Salt Sensitivity” [Journal of Medicine (1997) 28:147–156] describes a study evaluating salt sensitivity (SENS) after a period of antihypertensive treatment. Ten hypertensive patients (diastolic blood pressure between 90 and 115 mmHg) were studied after at least 18 months on antihypertensive treatment. SENS readings, which were obtained before and after the patients were placed on an antihypertensive treatment, are given here.

Chapter 6.9, Problem 28E, The paper “Effect of Long-Term Blood Pressure Control on Salt Sensitivity” [Journal of Medicine

  1. a. Is there significant evidence that the mean SENS value decreased after the patient received antihypertensive treatment?
  2. b. Estimate the size of the change in the mean SENS value.
  3. c. Do the conditions required for using the t procedures appear to be valid for these data? Justify your answer.
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The paper “Effect of Long-Term Blood Pressure Control on Salt Sensitivity” [Journal of Medicine (1997) 28:147–156] describes a study evaluating salt sensitivity (SENS) after a period of antihypertensive treatment. Ten hypertensive patients (diastolic blood pressure between 90 and 115 mmHg)were studied after at least 18 months on antihypertensive treatment. SENS readings, which wereobtained before and after the patients were placed on an antihypertensive treatment, are given here. Is there significant evidence that the mean SENS value decreased after the patient received antihypertensive treatment?
The paper “Effect of long-term blood pressure control on salt sensitivity” [Journal of Medicine (1997) 28:147–156] describes a study evaluating salt sensitivity (SENS) after a period of antihypertensive treatment. Ten hypertensive patients (diastolic blood pressure between 90 and 115 mmHg) were studied after at least 18 months on antihypertensive treatment. SENS readings, which were obtained before and after the patients were placed on an antihypertensive treatment, are given in data 3. Is there significant evidence that the mean SENS value decreased after the patient received antihypertensive treatment? data 3 'Before'        'After'22.86             6.117.74              -4.0215.49              8.049.97                3.291.44               -0.779.39                 6.9911.4               10.191.86                 2.09-6.71               11.46.42                10.7
The paper “Effect of long-term blood pressure control on salt sensitivity” [Journal of Medicine (1997) 28:147–156] describes a study evaluating salt sensitivity (SENS) after a period of antihypertensive treatment. Ten hypertensive patients (diastolic blood pressure between 90 and 115 mmHg) were studied after at least 18 months on antihypertensive treatment. SENS readings, which were obtained before and after the patients were placed on an antihypertensive treatment, are given in the table.  'Before' 'After' 22.86 6.11 7.74 -4.02 15.49 8.04 9.97 3.29 1.44 -0.77 9.39 6.99 11.4 10.19 1.86 2.09 -6.71 11.4 6.42 10.7 a) Write the null and alternate hypotheses What test will be used to test the hypothesis and what assumptions are required? test them. Is there significant evidence that the mean SENS value decreased after the patient received antihypertensive treatment?

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