Study Guide for Gould's Pathophysiology for the Health Professions
Study Guide for Gould's Pathophysiology for the Health Professions
6th Edition
ISBN: 9780323414142
Author: Hubert BS, Robert J; VanMeter PhD, Karin C.
Publisher: Saunders
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Chapter 6, Problem 1P
Summary Introduction

To describe: The way in which specific growth needs of a bacterium may determine the infection site in the host.

Introduction: Microbiology is the study of microorganisms. Microorganisms are small living forms that are visible only with the help of a microscope. Bacteria, fungi, virus, and protozoa are the main classification of microorganisms.

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Explanation of Solution

Infection occurs when the pathogen enters the body and starts their replications. The growth of bacteria in the host cell is based on many factors. For example, Clostridium tetani lives in anaerobic condition and it causes deep tissue infections.

Infections may not occur after the entry of microbes, which is due to the reasons as follows:

The site of infection of an organism is determined by the growth factors such as

pH:

  • Neutrophiles grow in a pH range of 5 to 8.
  • Acidophiles grow at a pH below 5.5.
  • Alkaliphiles grow best at a pH above 8.5.

Oxygen:

  • Obligate aerobes grow only in the presence of oxygen.
  • Microaerophiles grows in lower concentration of oxygen.
  • Obligate anaerobes grow only in the absence of oxygen.
  • Facultative anaerobes can make use of oxygen in the aerobic environment and fermentation or anaerobic respiration in an anaerobic environment.

Carbohydrates:

  • Photoautotrophic organisms use light as energy source and carbon dioxide as carbon source.
  • Chemoautotrophs such as Sulfolobus bacteria derive energy from inorganic chemical sources, such as H2S, NH3, or Fe2+ to utilize the carbon compounds.
  • Photoheterotrophs utilize the organic compounds for their nutrition in the presence of light. This peculiar mode is unique to some aquatic and salt loving prokaryotes bacteria, such as Rhodobacter and Chloroflexus.
  • Chemohetrotrophs derive the energy from organic compounds and utilize the carbon from organic compounds for their nutrition. This type of nutrition is peculiar in Clostridium and protists.

Temperature:

  • Psychrophiles: They are cold loving bacteria.
  • Mesophiles: Mesophiles grow in a moderate temperature between 45°C and 70°C.
  • Thermophiles: Thermophiles are heat loving bacteria that grow in temperature between 70°C and 110°C.
  • Hyperthermophiles: They grow at very high temperature.

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