Pharmacology and the Nursing Process, 8e
Pharmacology and the Nursing Process, 8e
8th Edition
ISBN: 9780323358286
Author: Linda Lane Lilley PhD RN, Shelly Rainforth Collins PharmD, Julie S. Snyder MSN RN-BC
Publisher: Elsevier Science
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Chapter 50, Problem 2NERQ
Summary Introduction

H2 receptor antagonists are also known as H2 blockers, they block the effect of histamine receptors, which are found in parietal cells. These cells secrete hydrochloric acid (HCl) in the stomach. Oversecretion of HCl may cause various gastrointestinal problems. The inhibition of histamine receptors by H2 receptor antagonists results in a reduced response of parietal cells to stimuli. This, in turn, leads to decreased acid secretion. About 90% of acid secretion can be suppressed by H2 receptor antagonists.

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