Fundamentals of General, Organic, and Biological Chemistry (8th Edition)
8th Edition
ISBN: 9780134015187
Author: John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher: PEARSON
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Chapter 5, Problem 5.75GP
Interpretation Introduction
Interpretation:
Many pharmaceuticals are marketed with the designation
Concept introduction:
Reactions of ionic compounds can be grouped into three and they are,
- 1. Precipitation reaction: A precipitation reaction takes place when two solutions of well soluble substances together form a poorly soluble salt.
- 2. Acid- base neutralization reaction: it is a double displacement reaction in which an acid and a base react to form an ionic compound (salt) and water.
- 3.
Oxidation-reduction reaction: Both the oxidation and reduction reaction occurs together in achemical reaction . It is also known as redox reaction.
The term solubility reveals the amount of a given substance that can be dissolved in a certain amount of solvent.
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Enalapril is an anti-hypertension “pro-drug” (i.e., a drug precursor) that isinactive until the ethyl ester (arrow in figure) is hydrolyzed by esterases present in blood plasma. The active drug is the dicarboxylic acid (“enalaprilat”) that results from this hydrolysis reaction.(a) Enalapril is administered in pill form, but enalaprilat must be administered intravenously. Why do you suppose enalapril works as a pill but enalaprilat does not? (b) Enalaprilat is a competitive inhibitor of the angiotensin-convertingenzyme (ACE), which cleaves the blood-pressure regulating peptideangiotensin I. ACE has a KM = 52 μM for angiotensin I, which is presentin plasma at a concentration of 75 μM. When enalaprilat is presentat 2.4 nM, the activity of ACE in plasma is 10% of its uninhibitedactivity. What is the value of K1 for enalaprilat?
Which of the following correctly identifies the products and reactants labeled in the image above?
Chapter 5 Solutions
Fundamentals of General, Organic, and Biological Chemistry (8th Edition)
Ch. 5.2 - Ozone (O3) is formed in the earths upper...Ch. 5.2 - Balance the following equations:...Ch. 5.2 - Prob. 5.3KCPCh. 5.3 - Many kidney stones are formed by precipitation of...Ch. 5.3 - Prob. 5.2CIAPCh. 5.3 - Predict the solubility of the following compounds:...Ch. 5.3 - Prob. 5.5PCh. 5.4 - Write and balance equations for the following...Ch. 5.5 - Prob. 5.7PCh. 5.5 - Prob. 5.8P
Ch. 5.5 - Prob. 5.9PCh. 5.6 - Prob. 5.3CIAPCh. 5.6 - The redox reaction that provides energy for the...Ch. 5.6 - Prob. 5.10PCh. 5.6 - Prob. 5.11PCh. 5.6 - For each of the reactions you identified as redox...Ch. 5.7 - Prob. 5.13PCh. 5.7 - Identify each of the tractions in Problem 5.13 as...Ch. 5.7 - For each traction in Problem 5.13 that you...Ch. 5 - Assume that the mixture of substances in drawing...Ch. 5 - Prob. 5.17UKCCh. 5 - Prob. 5.18UKCCh. 5 - Prob. 5.19UKCCh. 5 - Prob. 5.20UKCCh. 5 - Prob. 5.22APCh. 5 - Why is it not possible to balance an equation by...Ch. 5 - Write balanced equations for the following...Ch. 5 - Prob. 5.25APCh. 5 - Which of the following equations are balanced?...Ch. 5 - Prob. 5.27APCh. 5 - Balance the following equations:...Ch. 5 - Prob. 5.29APCh. 5 - When organic compounds are burned, they react with...Ch. 5 - Prob. 5.31APCh. 5 - Hydrofluoric acid (HF) is used to etch glass...Ch. 5 - Write a balanced equation for the reaction of...Ch. 5 - Identify each of the following reactions as a...Ch. 5 - Write balanced ionic equations and net ionic...Ch. 5 - Write balanced ionic equations and net ionic...Ch. 5 - Prob. 5.37APCh. 5 - Prob. 5.38APCh. 5 - Which of the following substances are likely to be...Ch. 5 - Which of the following substances are likely to be...Ch. 5 - Use the solubility guidelines in Section 5.3 to...Ch. 5 - Use the solubility guidelines in Section 5.3 to...Ch. 5 - Prob. 5.43APCh. 5 - Prob. 5.44APCh. 5 - Prob. 5.45APCh. 5 - Prob. 5.46APCh. 5 - Where in the periodic table are the best reducing...Ch. 5 - Prob. 5.48APCh. 5 - Prob. 5.49APCh. 5 - Prob. 5.50APCh. 5 - Prob. 5.51APCh. 5 - Assign an oxidation number to the metal in the...Ch. 5 - Prob. 5.53APCh. 5 - Which element is oxidized and which is reduced in...Ch. 5 - Prob. 5.55APCh. 5 - Prob. 5.56APCh. 5 - Prob. 5.57APCh. 5 - Identify the oxidizing agent and the reducing...Ch. 5 - Prob. 5.59CPCh. 5 - Prob. 5.60CPCh. 5 - Prob. 5.61CPCh. 5 - Prob. 5.62CPCh. 5 - Prob. 5.63CPCh. 5 - Prob. 5.64CPCh. 5 - Prob. 5.65CPCh. 5 - Prob. 5.66CPCh. 5 - Hard water contains magnesium and calcium ions...Ch. 5 - Prob. 5.68CPCh. 5 - Prob. 5.69CPCh. 5 - Prob. 5.70CPCh. 5 - Geologists identify carbonate minerals by reaction...Ch. 5 - Prob. 5.72CPCh. 5 - High temperature combustion processes, such as in...Ch. 5 - Milk of magnesia is an over-the-counter product...Ch. 5 - Prob. 5.75GP
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