Essentials of Biology (5th International Edition)
5th Edition
ISBN: 9781259660269
Author: Sylvia S. Mader, Dr., Michael Windelspecht
Publisher: Mcgraw-Hill
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Chapter 5, Problem 2TC
Cystic fibrosis is a genetic disorder that results in a defective membrane transport protein .The defective protein closes chloride ion channels in membranes, preventing chloride ions from being exported out of cells. This results in the development of a thick mucus on the outer surfaces of cells. This mucus clogs the ducts that carry digestive enzymes from the pancreas to the small intestine, clogs the airways in the lungs, and promotes lung infections. Why do you think the defective protein results in a thick, sticky mucus outside the cells, instead of a loose, fluid covering?
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Tight junctions are protein junctions that provide a water-tight seal between cells. They ensure that materials must enter the cells (through diffusion or active transport) to pass through the tissue. Tight junctions are characteristic of cells lining the digestive tract, where materials are required to pass through cells (not between them) before they can travel into the blood.
Can someone explain more clearly why lining the digestive tract?
Proteins that are trafficked through the secretory pathway of eukaryotic cells are never exposed directly to the cytoplasm. Which of the following is the best explanation for why this is true?
A. Cells that specialize in protein secretion lack cytoplasm, because protein synthesis machinery takes up the volume of the cell instead.
B. For a protein that will be secreted, during the whole time that it spends inside of the cell, it is enclosed within other membrane-bound compartments.
C. While a protein is in the secretory pathway, it is surrounded by a dense cloud of ions that protect it from the cytoplasm.
D. A protein that will be secreted is not synthesized by ribosomes in the cytoplasm; instead, it is synthesized by proteins at the plasma membrane and fed directly into the extracellular space.
Some cells in the pancreatic acinus form vesicles containing zymogens. Then the cells secrete the zymogens. Certain proteins called v-SNARES play a role in this process. What best describes the proteins called v-SNARES?
a.) v-SNARES are proteins on the cytosolic face of the plasma membrane that help vesicles to fuse with the plasma membrane
b.) v-SNARES are a type of glycosphingolipid in the vesicle lipid bilayer that help maintain vesicle integrity
c.) v-SNARES are proteins on the surface of vesicles that help the vesicle fuse with the cytosolic face of the plasma membrane
d.) v-SNARES are proteins contained inside of vesicles that help stabilize the vesicle contents until the vesicle fuses with the cytosolic face of the plasma membrane
Chapter 5 Solutions
Essentials of Biology (5th International Edition)
Ch. 5.1 - Prob. 5.1LOCh. 5.1 - Prob. 1LOCh. 5.1 - Prob. 2LOCh. 5.1 - Prob. 3LOCh. 5.1 - Prob. 1CYPCh. 5.1 - Prob. 2CYPCh. 5.1 - Prob. 3CYPCh. 5.1 - Prob. 1ACh. 5.1 - Prob. 2ACh. 5.1 - Prob. 3A
Ch. 5.2 - Prob. 1LOCh. 5.2 - Prob. 2LOCh. 5.2 - Prob. 3LOCh. 5.2 - Prob. 1CYPCh. 5.2 - Prob. 2CYPCh. 5.2 - Prob. 3CYPCh. 5.2 - Identify the incorrect statement a. When ATP...Ch. 5.2 - Prob. 5ACh. 5.3 - Illustrate how metabolic reactions are catalyzed...Ch. 5.3 - Identify the role that enzymes play in metabolic...Ch. 5.3 - Prob. 3LOCh. 5.3 - Prob. 4LOCh. 5.3 - Prob. 5LOCh. 5.3 - Prob. 1CYPCh. 5.3 - Prob. 2CYPCh. 5.3 - Summarize the benefit of using feedback inhibition...Ch. 5.3 - 6. In the induced fit model of enzyme action,
a....Ch. 5.3 - Prob. 7ACh. 5.3 - Prob. 8ACh. 5.4 - Prob. 1LOCh. 5.4 - Prob. 2LOCh. 5.4 - Prob. 3LOCh. 5.4 - Prob. 4LOCh. 5.4 - Prob. 5LOCh. 5.4 - Prob. 1CYPCh. 5.4 - Prob. 2CYPCh. 5.4 - Prob. 3CYPCh. 5.4 - Prob. 4CYPCh. 5.4 - Prob. 9ACh. 5.4 - Prob. 10ACh. 5.4 - Match the items to the correct answers in the key....Ch. 5.4 - Prob. 12ACh. 5.4 - Prob. 13ACh. 5.4 - Prob. 14ACh. 5.4 - Prob. 15ACh. 5 - Prob. 1BYBCh. 5 - Prob. 2BYBCh. 5 - Prob. S1.1BYBCh. 5 - Section 3.2 What are the four levels of structure...Ch. 5 - Prob. S4.2BYBCh. 5 - Prob. 1TCCh. 5 - Cystic fibrosis is a genetic disorder that results...Ch. 5 - Prob. 3TC
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