Concept explainers
Interpretation:
The three-dimensional formulas for isomers of the given drugs are to be drawn.
Concept introduction:
A dashed wedge is used to represent a bond, which projects behind the plane of the paper.
A solid wedge is used to represent a bond, which projects out of the plane of the paper.
An ordinary line is used to represent a bond, which lies in the plane of the paper.
In order to draw the three-dimensional formula of molecules, first, draw as many carbon atoms in the plane of the paper as possible with the help of ordinary lines. Then, the substituent groups or hydrogen will be represented by using dashed or solid wedge bonds.
When the order of progression from the group of highest priority to that of the next highest priority is clockwise, it is said to be the (R) configuration
When the order of progression from the group of highest priority to that of the next highest priority is anticlockwise, then it is said to be the (S) configuration.
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Organic Chemistry
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