Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 47, Problem 47.3CR
Suppose you found two classes of mouse mutations, one that .affected limb development only and one that affected both limb and kidney development. Which class would be more likely to alter the function of monocilia? Explain.
Expert Solution & Answer
Trending nowThis is a popular solution!
Students have asked these similar questions
Suppose you found two classes of mouse mutations, one that affectedlimb development only and one that affected both limb and kidneydevelopment. Which class would be more likely to alter the functionof monocilia? Explain.
You are studying a mutation in mice, which acts dominantly. Mice that have only one copy of the allele carrying this mutation have a kinky tail phenotype. You identify the gene that the mutation affects and find that the codon that encodes the second amino acid in the predicted protein has been mutated to a stop codon. Would you characterize this mutation as a loss-of-function or a gain-of-function and what specific subtype (hypermorphic, antimorphic, etc. ) within these categories? Explain your reasoning.”
given a situation in which you manipulated a zebrafish embryo by injecting high levels of retinoic acid so that no anterior genes will be expressed. Surprisingly, after embryonic development, you are still able to observed the presence of anterior structures. What could explain this observation? What changes in your experiment would you make to achieve your objective?
Chapter 47 Solutions
Campbell Biology
Ch. 47.1 - How does the fertilization envelope form in sea...Ch. 47.1 - Prob. 2CCCh. 47.1 - MAKE CONNECTIONS Review Figure 12.16 on cell...Ch. 47.2 - In the frog embryo, convergent extension elongates...Ch. 47.2 - WHAT IF? Predict what would happen if Ca2+ was...Ch. 47.2 - MAKE CONNECTIONS Unlike some other types of birth...Ch. 47.3 - Prob. 1CCCh. 47.3 - Prob. 2CCCh. 47.3 - Prob. 3CCCh. 47.3 - Prob. 4CC
Ch. 47 - What cell-surface event would likely fail if a...Ch. 47 - What are some functions of apoptosis in...Ch. 47 - Suppose you found two classes of mouse mutations,...Ch. 47 - Prob. 1TYUCh. 47 - Which of the following is common to the...Ch. 47 - The archenteron develops into a. the mesoderm. b....Ch. 47 - What structural adaptation in chickens allows them...Ch. 47 - Prob. 5TYUCh. 47 - In humans, identical twins are possible because a....Ch. 47 - Cells transplanted from the neural tube of a frog...Ch. 47 - DRAW IT Each blue circle in the figure below...Ch. 47 - EVOLUTION CONNECTION Evolution in insects and...Ch. 47 - Prob. 10TYUCh. 47 - Prob. 11TYUCh. 47 - Prob. 12TYUCh. 47 - SYNTHESIZE YOUR KNOWLEDGE Occasionally, two-headed...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Given the following schematic for a gene and its associated regulatory regions, answer the following questions by placing the correct letter in the provided blanks please put in the correct letter for the questions What region would provide cell type-specific expression of genes? region What site would significantly increase gene expression rates? = region What region or regions of this gene’s coding sequence are expressed as amino acids = regionarrow_forwardIn the gene in the fruit fly (Drosophila) called antennepedia. It controls the formation of which structures? What happens when it is mutated?arrow_forwardSynpolydactyly is an abnormality characterized by webbing between partially or completely duplicated fingers or toes (Figure 18.15). The same mutations that cause the human phenotype give rise to a similar phenotype in mice. In what family of genes do you think these mutations occur?arrow_forward
- Proteins A,B,C, and D in the diagram are encoded by different genes and interact with each other. Imagine that a mutation in the gene for protein A changes one of the charged amino acid in the red circle area from positive to negative charge (blue arrow). this mutation results in a mutant phenotype. Assume a mutation in the gene for protein B occurs and the double mutants have a phenotype that is almost wild type. How would you best describe the mutation in gene B? Protein C Proten A Protein B Protein B Wild type Mutation in the gene for protein Aarrow_forwardIn the nematode C. elegans, some worms have blisteredcuticles due to a recessive mutation in one of the bligenes. Someone studying a suppressor mutation thatsuppressed bli-3 mutations wanted to know if it wouldalso suppress mutations in bli-4. They had a strain thatwas homozygous for this recessive suppressor mutation,and its phenotype was wild type.a. How would they determine whether this recessivesuppressor mutation would suppress mutations in bli-4?In other words, what is the genotype of the wormsrequired to answer the question?b. What cross(es) would they do to make these worms?c. What results would they expect in the F2 if(1) it did act as a suppressor of bli-4?(2) it did not act as a suppressor of bli-4?arrow_forwardThe figure below represents a cell undergoing gene expression. Use the figure to answer the questions that follow (a - e). a. What is indicated by label (2) in the figure above? b. What is indicated by label (3) in the figure above? c. What happens to the part labelled (3) and what complex makes it happen? d. Which amino acid is represented by (6)? e. Give the one anticodon in the 5' to 3' direction that will recognize all the codons for this amino acid in (c)arrow_forward
- You hope to study a gene that codes for a neurotransmitter protein produced in human brain cells. You know the amino acid sequence of the protein. Explain how you might (a) identify what genes are expressed in a specific type of brain cell, (b) identify (and isolate) the neurotransmitter gene, (c) produce multiple copies of the gene for study, and (d) produce large quantities of the neurotransmitter for evaluation as a potential medication.arrow_forwardThe homeotic mutation Antennapedia causes mutant Drosophila to have legs in place of antennae and is a dominant gain-of-function mutation. List all the properties of such mutations. How does the Antennapedia gene change antennae into legs?arrow_forwardLike Hurler syndrome, Fabry disease involves an abnormal accumulationof substances within lysosomes. However, the lysosomes of individuals with Fabry disease show an abnormal accumulation of lipids. The defective enzyme is α-galactosidase A, which is a lysosomal enzyme that functions in lipid metabolism. The defect causes cell damage, especially to the kidneys, heart, and eyes. The gene that encodes α-galactosidase A is found on the X chromosome. Let’s suppose a phenotypically unaffected couple producestwo sons with Fabry disease and one phenotypically unaffecteddaughter. What is the probability that the daughter will have anaffected son?arrow_forward
- Many aspects of gene function can be nicely explained with the one-gene-one-enzyme hypothesis, which states that a gene controls the production of an enzyme. Which of the following findings about gene expression, though, requires an expansion of this simple concept? Choose an answer below: Non-enzyme proteins are made from genes too. Some genes code for RNA molecules only. Enzymes composed of different polypeptides are coded for by more than one gene. a and c, but not b a, b, and carrow_forwardThe rb gene encodes a protein that inhibits E2F, a transcriptionfactor that activates several genes involved in cell division.Mutations in rb are associated with certain forms of cancer,such as retinoblastoma. Under each of the following conditions,would you expect the cancer to occur?A. One copy of rb is defective; both copies of E2F are functional.B. Both copies of rb are defective; both copies of E2F arefunctional.C. Both copies of rb are defective; one copy of E2F is defective.D. Both copies of rb and E2F are defective.arrow_forwardYou are interested in the effects of mutations on the expression of a human protein- encoding gene expressed in skin cells. The gene has one intron that is 450 nucleotides long. After this intron is removed from the pre-mRNA, the mRNA transcript is 1100 nucleotides in length. Diploid somatic cells have two copies of this gene. Predict the size and amount of mRNA from the cytosol of skin cells, which were obtained from the following individuals: • Individual 1: Normal individual with no mutations in this gene. • Individual 2: Homozygous for a deletion that removes the -10 to -100 region of the gene that encodes this mRNA. • Individual 3: Heterozygous in which one gene is normal and the other gene has a deletion that removes the -10 to -100 region. • Individual 4: Homozygous for a five-nucleotide deletion in the intron that removes the GT sequence at the 5' splice site. Explain your answers.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY