Life: The Science of Biology
Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
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Chapter 46.2, Problem 2R
Summary Introduction

To review:

The reasons why a greater response is generated in the retinal ganglion cell by a small spot of light falling on the retina than a large spot of light.

Introduction:

Retinal ganglion cells are neurons located near the retina of eye. They receive information from the photoreceptor cells and transmit action potentials to the thalamus and the visual cortex of the brain. The brain processes this information and sends signals which make vision possible.

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The correct pathway of activation (by sending neuronal signals) in the retina is bipolar cell - retinal ganglion cell - photoreceptor photoreceptor - retinal ganglion cell - bipolar cell retinal ganglion cell - bipolar cell - photoreceptor photoreceptor - bipolar cell - retinal ganglion cell O bipolar cell - photoreceptor - amacrine cell
The best characterization of receptive fields in retinal ganglion cells that respond best to light-dark contrast is that for a cell that responds to light it has no response to light in its center on field for a cell that responds to light it has a strong response to light in the surround field for a cell that responds to light it has a strong response to light in its center on field for a cell that responds to light it has a weak response to light in its center on field
A scientist has dissected out a small section of the retina and is able to directly record the action potential firing rate in a single ganglion cell.  Assume there is a on-center off-surround bipolar cell connected to an on-center off-surround ganglion cell.  When applying ‘Stimulus 1’ the scientist records a moderate action potential rate. When applying ‘Stimulus 2’ the rate of action potentials increases substantially. In the context of this experiment no illumination is an option as a 'Stimulus'.  ‘Stimulus 2’ would result in what response in the bipolar cell (the one connected to the ganglion cell the scientist is measuring)? A. A large depolarization of the bipolar cell membrane    B. The bipolar cell membrane would remain at the resting membrane potential    C. A large hyperpolarization of the bipolar cell membrane    D. A small hyperpolarization of the bipolar cell membrane    E. A small depolarization of the bipolar cell membrane
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