Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 42, Problem 22CTQ
Different MHC I molecules between donor and recipient cells can lead to rejection of a transplanted organ or tissue. Suggest a reason for this.
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Different MHC I molecules between donor and recipient cells can lead to rejection of a transplanted organ or tissue. Explain relevant concepts in relation to tissue rejection in organ transplant.
If transplanting a solid organ such as a kidney, why is MHC II matching also important to success of the graft?
Explain the difference between the two ways that alloreactive T cells can be stimulated in an acute transplant rejection (what’s happening?)
Chapter 42 Solutions
Biology 2e
Ch. 42 - Figure 42.11 Which of the following statements...Ch. 42 - Figure 42.14 Based on what you know about MHC...Ch. 42 - Figure 42.16 The Rh antigen is found on Rh...Ch. 42 - Which of the following is a barrier against...Ch. 42 - Although interferons have several effects, they...Ch. 42 - Which organelle do phagocytes use to digest...Ch. 42 - Which innate immune system component uses MHC I...Ch. 42 - Which of the following is both a phagocyte and an...Ch. 42 - Which immune cells bind MHC molecules on APCs via...Ch. 42 - What “self” pattern is identified by NK cells?...
Ch. 42 - The acquired ability to prevent an unnecessary or...Ch. 42 - A memory B cell can differentiate upon reexposure...Ch. 42 - Foreign particles circulating in the blood are...Ch. 42 - The structure of an antibody is similar to the...Ch. 42 - The first antibody class to appear in the serum in...Ch. 42 - What is the most abundant antibody class detected...Ch. 42 - Breastfed infants typically are resistant to...Ch. 42 - Allergy to pollen is classified as: an autoimmune...Ch. 42 - A potential cause of acquired autoimmunity is...Ch. 42 - Autoantibodies are probably involved in: reactions...Ch. 42 - Which of the following diseases is not due to...Ch. 42 - Different MHC I molecules between donor and...Ch. 42 - If a series of genetic mutations prevented some,...Ch. 42 - Explain the difference between an epitope and an...Ch. 42 - What is a naïve B or T cell?Ch. 42 - How does the Th1 response differ from the Th2...Ch. 42 - In mammalian adaptive immune systems, T cell...Ch. 42 - How do B and T cells differ with respect to...Ch. 42 - Why is the immune response after reinfection much...Ch. 42 - What are the benefits and costs of antibody cross...
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- T cells have to work in a partnership with an Antigen Presenting Cell (APC). Before this can occur, the APC must modify the antigen. Please discuss how this process happens and the major protein that is involved. Be detailed.arrow_forwardExplain the term immunoglobulin (IG).arrow_forwardDiscuss the potential side effect of the drugs cyclosporineand tacrolimus, which function by inhibiting cytokine production (rather than inhibiting specific responses to transplanted organs).arrow_forward
- Sketch a diagram to illustrate the interaction between MHC I molecules of the named cell type and the TCR receptor at the cell surface of the corresponding cell type.arrow_forwardWhy is it important to monitor the T lymphocytes in someone with AIDS?arrow_forwardPhagocytes bind to pathogen-associated molecular patterns (PAMPs) via: I selected opsonins, which is incorrect. Please help.arrow_forward
- Describes the relationship of the following terms using short terms: Adhesion Molecule(s)Anergic T cellAntigen PresentationAntigen Processingarrow_forwardDescribe Class I MHC pathway of antigen processing and presentation. Highlight the functions of the structures and organelles associated with the pathway. Illustrate with a diagram.arrow_forwardWrite T if the statement is correct; write F if the statement is not correct. P and E selectins are expressed by endothelial cells. " " TCRs consist of heavy and light chains. " " A disulfide bond can be found on TCRs. " " The antigen binding site in TCRs is contributed by the variable region of the H chain and the variable region of the light chain. " " CD4, but not CD8, interacts with Lck. " "arrow_forward
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