Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 42, Problem 22CTQ
Different MHC I molecules between donor and recipient cells can lead to rejection of a transplanted organ or tissue. Suggest a reason for this.
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Different MHC I molecules between donor and recipient cells can lead to rejection of a transplanted organ or tissue. Explain relevant concepts in relation to tissue rejection in organ transplant.
If transplanting a solid organ such as a kidney, why is MHC II matching also important to success of the graft?
Explain the difference between the two ways that alloreactive T cells can be stimulated in an acute transplant rejection (what’s happening?)
Chapter 42 Solutions
Biology 2e
Ch. 42 - Figure 42.11 Which of the following statements...Ch. 42 - Figure 42.14 Based on what you know about MHC...Ch. 42 - Figure 42.16 The Rh antigen is found on Rh...Ch. 42 - Which of the following is a barrier against...Ch. 42 - Although interferons have several effects, they...Ch. 42 - Which organelle do phagocytes use to digest...Ch. 42 - Which innate immune system component uses MHC I...Ch. 42 - Which of the following is both a phagocyte and an...Ch. 42 - Which immune cells bind MHC molecules on APCs via...Ch. 42 - What “self” pattern is identified by NK cells?...
Ch. 42 - The acquired ability to prevent an unnecessary or...Ch. 42 - A memory B cell can differentiate upon reexposure...Ch. 42 - Foreign particles circulating in the blood are...Ch. 42 - The structure of an antibody is similar to the...Ch. 42 - The first antibody class to appear in the serum in...Ch. 42 - What is the most abundant antibody class detected...Ch. 42 - Breastfed infants typically are resistant to...Ch. 42 - Allergy to pollen is classified as: an autoimmune...Ch. 42 - A potential cause of acquired autoimmunity is...Ch. 42 - Autoantibodies are probably involved in: reactions...Ch. 42 - Which of the following diseases is not due to...Ch. 42 - Different MHC I molecules between donor and...Ch. 42 - If a series of genetic mutations prevented some,...Ch. 42 - Explain the difference between an epitope and an...Ch. 42 - What is a naïve B or T cell?Ch. 42 - How does the Th1 response differ from the Th2...Ch. 42 - In mammalian adaptive immune systems, T cell...Ch. 42 - How do B and T cells differ with respect to...Ch. 42 - Why is the immune response after reinfection much...Ch. 42 - What are the benefits and costs of antibody cross...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- why is MALT considered strategically placed?arrow_forwardExplain why immunosuppressive drugs should be taken on aregular and permanent basis following a transplant.arrow_forwardThere is a variety of organs routinely transplanted in clinical medicine. Knowing that organ transplantation is routinely performed in clinic answer the following: What is a significance of HLA-typing used to match with the most suitable recipient? What has been achieved by using powerful immunosuppressive drugs?arrow_forward
- Pus is both a sign of infection and an indicator ofimmune defenses in action. Explain.arrow_forwardDescribe the difference between (A) ‘naked antibodies’ and (B) conjugated antibodies in the context of using humanized monoclonal antibodies for tumor killing.arrow_forwardT cells have to work in a partnership with an Antigen Presenting Cell (APC). Before this can occur, the APC must modify the antigen. Please discuss how this process happens and the major protein that is involved. Be detailed.arrow_forward
- Why are MHC proteins so highly variable?arrow_forwardIn terms of antigens and antibodies, explain why O- is considered a universal donor and why AB+ is considered a universal recipient. Even so, why can’t whole blood O- be donated to a person of type AB+ blood?arrow_forwardExplain the term immunoglobulin (IG).arrow_forward
- In the event of an inflammation in the body, discuss the vaccine concept after indicating how the proteins that cause this formation in the cell where the inflammation occurs and therefore cause the initiation of the fight against this foreign substance.arrow_forwardDiscuss the potential side effect of the drugs cyclosporineand tacrolimus, which function by inhibiting cytokine production (rather than inhibiting specific responses to transplanted organs).arrow_forwardSketch a diagram to illustrate the interaction between MHC I molecules of the named cell type and the TCR receptor at the cell surface of the corresponding cell type.arrow_forward
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