Organic Chemistry - Standalone book
10th Edition
ISBN: 9780073511214
Author: Francis A Carey Dr., Robert M. Giuliano
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Question
Chapter 4.13, Problem 24P
Interpretation Introduction
Interpretation:
The configuration of the more soluble component of the mixture of diastereomeric salts of
Concept introduction:
Diastereomers have more than one chirality centers and are not the mirror images of each other.
Diastereomers have different chemical and physical properties.
The configuration of at least one chirality center is the same in two diastereomers.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Briefly answer the following Questions
1. What is the commercial use of ibuprofen?
2. What are the important criteria of a good resolving agent in the resolution of ibuprofen?
3. In particular why is (S)-methylbenzylamine a suitable resolving agent for ibuprofen?
Explain briefly the differences in Rf values of the pigments that you have separated from spinach juice. What properties must the pigment have to travel further in the chromatogram?
Consider the structures of cholesterol and ?-carotene. Which do you think will have the highest Rf value if the solvent used was acetone - hexane (20:80)? Why?
(b) Define
example for each :
the following
and
provide
(i) Chromophore and auxochrome
(i) Red shift and blue shift
Chapter 4 Solutions
Organic Chemistry - Standalone book
Ch. 4.2 - Examine the following for chirality centers:Ch. 4.2 - Prob. 2PCh. 4.3 - Prob. 3PCh. 4.3 - Prob. 4PCh. 4.4 - Prob. 5PCh. 4.4 - Prob. 6PCh. 4.5 - Does the molecular model shown represent...Ch. 4.6 - Assign absolute configurations as R or S to each...Ch. 4.6 - Draw three-dimensional representations ofCh. 4.7 - Prob. 10P
Ch. 4.7 - Using the Fischer projection of (R)-2-butanol...Ch. 4.8 - Prob. 12PCh. 4.9 - Prob. 13PCh. 4.9 - Prob. 14PCh. 4.10 - Prob. 15PCh. 4.10 - Draw Fischer projections of the four...Ch. 4.10 - Prob. 17PCh. 4.11 - A meso stereoisomer is possible for one of the...Ch. 4.11 - One of the stereoisomers of...Ch. 4.12 - Prob. 20PCh. 4.12 - Prob. 21PCh. 4.13 - Prob. 22PCh. 4.13 - Prob. 23PCh. 4.13 - Prob. 24PCh. 4.14 - Prob. 25PCh. 4 - Prob. 26PCh. 4 - Including stereoisomers, write structural formulas...Ch. 4 - Prob. 28PCh. 4 - Prob. 29PCh. 4 - Prob. 30PCh. 4 - Prob. 31PCh. 4 - Prob. 32PCh. 4 - Prob. 33PCh. 4 - Prob. 34PCh. 4 - Prob. 35PCh. 4 - Prob. 36PCh. 4 - Prob. 37PCh. 4 - Prob. 38PCh. 4 - Prob. 39PCh. 4 - (-)-Menthol is the most stable stereoisomer of...Ch. 4 - Prob. 41PCh. 4 - Prob. 42PCh. 4 - (a) An aqueous solution containing 10 g of...Ch. 4 - Prob. 44DSPCh. 4 - Prob. 45DSPCh. 4 - Consider two chemical changes: one occurring at a...Ch. 4 - Consider two chemical changes: one occurring at a...Ch. 4 - Prob. 48DSPCh. 4 - Consider two chemical changes: one occurring at a...Ch. 4 - Consider two chemical changes: one occurring at a...
Knowledge Booster
Similar questions
- How would the experiment of resolution of ibuprofen change if a student instead used racemic methylbenzylamine?( Explain what would change and why.)arrow_forwardIf the TLC eluent increases in polarity, what will happen to the Rf value of acetaminophen and phenacetin? Explain.arrow_forwardSpecifically how would the resolution of ibuprofen experiment change if a student used (R)-methylbenzylamine instead of (S)-methylbenzylamine? Explain what would change and why.arrow_forward
- Calculate k, the degradation rate constant, responsible for drug degradation in this solution (in month-1).arrow_forwardWhy is it necessary to resolve chiral pharmaceuticals (why cant we just use racemic versions)? What are the important criteria of a good resolving reagent? In particular why is (S)- methylbenzylamine a suitable resolving agent for ibuprofenarrow_forwardDraw the molecular structure of glycerol-1-linolenate-2-palmitate-3-eliadate and calculate its theoretical iodine value and saponification number. Of what relevance is the latter?arrow_forward
- Assign the peaks in IR spectrum of Aspirin and the functional greoup band is dissociated with.arrow_forwardDraw a well labeled outline showing how the resolution of ibuprofen process worked and then fully draw out the specific reactions used in the separation process?arrow_forwardQuestion: What is the theoretical basis for the separation of enantiomers using chiral chromatography, and what factors influence the resolution of enantiomeric peaks?arrow_forward
- Why does a 70:30 hexane:acetone mixture produce a more effective separation of pigments in spinach compared to a 50:50 hexane:acetone mixture? Explain thoroughlyarrow_forwardi) Calculate the selectivity factor, , for the separation of the two enantiomers.(ii) Calculate the resolution, RS, of the pair of peaks corresponding to the two enantiomersof the medicine. (iii) Suggest two modifications that could be made to the analytical method describedabove with the aim of increasing the observed value of RS. Briefly explain your choicesand indicate any likely disadvantages of your proposed modifications. (iv) A non-racemic sample of the medicine gave peaks with retention times of 6.42 min(98.8% relative area) and 5.61 min (1.2% relative area). Calculate the enantiomericexcess of this second sample, stating any assumptions that you make.arrow_forward(a) On performing a tlc of the reaction product of borohydride reduction on a plate alongside pure benzophenone, a student observed two spots in their product, the stronger corresponding to the benzophenone. What conclusion can be drawn? (b) What is the stationary phase on the tlc plate and why is it effective as a stationary phase?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Macroscale and Microscale Organic ExperimentsChemistryISBN:9781305577190Author:Kenneth L. Williamson, Katherine M. MastersPublisher:Brooks Cole
Macroscale and Microscale Organic Experiments
Chemistry
ISBN:9781305577190
Author:Kenneth L. Williamson, Katherine M. Masters
Publisher:Brooks Cole