Campbell Essential Biology with Physiology (6th Edition)
6th Edition
ISBN: 9780134711751
Author: Eric J. Simon, Jean L. Dickey, Jane B. Reece
Publisher: PEARSON
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Chapter 4, Problem 15PS
Interpreting Data A population of bacteria may evolve resistance to a drug over time. Draw a graph that represents such a change. Label the x-axis as “time” and the y-axis as “population size.” Draw a line on the graph that represents how the
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Paragraph
Drawing
The previous scenario is a greatly-simplified demonstration of how antibiotic resistance is selected for in bacteria.
It assumes bacterial cells are either totally resistant (BR+, red cells) or completely susceptible (BRo, yellow). In
reality, just like people differ in height, with many different heights possible, bacteria in a population can differ
along a whole spectrum of resistance.
Drag and Drop these labels on to the graph. One
label will not be used
Least Resistant
Use of
Use of
brincomycin
selects AGAINST
brincomycin
selects FOR
these cells
these cells
Spectrum of
Resistance
Number of cells
Most Resistant
Notes
Comments
33°F
The Kishony performed a simple but elegant experiment using a “mega-plate.”
Which of the following is a fair conclusion that can be drawn from this study?
The majority of antibiotic resistance occurs via horizontal gene transfer (HGT) between Actinobacteria
Sensitive bacteria may acquire resistance to high concentrations of the antibiotic through many mutations
Bacteria will gradually lose resistance to an antibiotic if you plate them on a large enough plate
Bacteria will migrate via chemotaxis away from recombinant phage used in phage therapy
There are concerns about overuse and misuse of antibacterial drugs, and the association of these with increased antibiotic resisstance in bacteria. Of the following, which best explains this?
Antibiotic exposure directly causes many of bacterial in a population to mutate and develop new antibiotic resistance traits.
If antibiotic use occurs repeatedly in a person, the dosage of the drug needs to be increased to work in a patient’s system because he/she will develop physiological tolerance to the antibiotic.
Exposure to an antibiotic causes bacteria to die or become stronger; stronger bacteria will be better able to cope with additional exposures to any antibiotic drug, eventually becoming immune to all antibiotics.
Antibiotics kill susceptible cells and even a small number of existing resistant bacteria that survive will become the majority of the population that remains, leading to populations that are resistant to this drug.
Chapter 4 Solutions
Campbell Essential Biology with Physiology (6th Edition)
Ch. 4 - You look into a microscope and view an unknown...Ch. 4 - Explain how each word in the term fluid mosaic...Ch. 4 - Identify which of the following structures...Ch. 4 - Prob. 4SQCh. 4 - Prob. 5SQCh. 4 - Name two similarities in the structure or function...Ch. 4 - Prob. 7SQCh. 4 - Prob. 8SQCh. 4 - Prob. 9SQCh. 4 - Prob. 10IMT
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