Loose Leaf For Integrated Principles Of Zoology
18th Edition
ISBN: 9781260411140
Author: Cleveland P Hickman Jr. Emeritus, Susan L. Keen, David J Eisenhour Professor PhD, Allan Larson, Helen I'Anson Associate Professor of Biology
Publisher: McGraw-Hill Education
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Chapter 33, Problem 5RQ
Explain different ways in which invertebrates and vertebrates have achieved high velocities for conduction of action potentials, can you suggest why the invertebrate solution would not be suitable for the homeorthermic birds and mammals?
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Figure 1 shows the action potential graph recorded from a rat neurone and the potential changes
obtained from the rat neurone when the concentration of potassium ([K*]out) and calcium
([Ca²+]out) are varied extracellularly in the bathing solution.
(i)
In the resting state, is the neuronal permeability to potassium more than, less than or equal
to that of the permeability to calcium? Explain your answer.
(ii)
Vm
'The calcium ion concentrations are lower inside the cell than outside.' Justify this
statement based on the graphs and the Nernst equation assuming the temperature is at 25 °C.
Vm
30
0
-30
30
0-
-30
0
50
AP overshoot
[K+ lout
100
150
time (msec)
30
RP
Figure 1
0-
-30
AP overshoot
RP
200
250
AP overshoot
{Ca²+ Jout
RP
Toxins such as tetrodotoxin (from puffer fish and newts) andsaxitoxin (from red-tide dinoflagellates) block voltage-gated Na+channels selectively. What effect would they have on currentsin a voltage clamp to 0 mV? How do you suppose such toxinsevolved?
The traces below show the action potential waveforms in an external
meidum of different concentrations of *
40
100%
50%
33%
40
1
2
time (msec)
calcium
chloride
potassium
O sodium
Chapter 33 Solutions
Loose Leaf For Integrated Principles Of Zoology
Ch. 33 - Define the following terms: neuron, axon,...Ch. 33 - Glial cells far outnumber neurons and contribute...Ch. 33 - The concentration of potassium ions inside a nerve...Ch. 33 - What ionic and electrical changes occur during...Ch. 33 - Explain different ways in which invertebrates and...Ch. 33 - Why is the sodium-potassium pump indirectly...Ch. 33 - Prob. 7RQCh. 33 - Prob. 8RQCh. 33 - Prob. 9RQCh. 33 - Prob. 10RQ
Ch. 33 - Prob. 11RQCh. 33 - Prob. 12RQCh. 33 - Prob. 13RQCh. 33 - Prob. 14RQCh. 33 - Chemoreception in vertebrates and insects is...Ch. 33 - What is the vomeronasal organ and what activity...Ch. 33 - Explain how ultrasonic detectors of certain...Ch. 33 - Outline the place theory of pitch discrimination...Ch. 33 - Explain how the semicircular canals of the ear are...Ch. 33 - Contrast the structure and functioning of the...Ch. 33 - Explain what happens when light strikes a...Ch. 33 - Prob. 22RQCh. 33 - Prob. 1FFT
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- The action potential generated in the squid giant axon requires voltage-gated potassium channels. Describe the shape of the action potential if these channels are blocked using TEA (Tetraethylammonium).arrow_forwardAcetylcholine is an excitatory neurotransmitter that is responsible for initiating muscle movement. Consider the scenario where a mouse was bitten by a snake that injected venom into their circulatory system. The venom has an inhibitory effect on the reuptake of acetylcholine from the synaptic cleft. Explain how the mouse’s body would respond to the venom as well as the venoms effect at the cellular level.arrow_forwardConduction velocity refers to the [a] at which an action potential travels along a neuron's axon. In invertebrates, conduction velocity can only be increased by [b]. However in vertebrates (exclusively), such as humans, conduction velocity can also be increased by [c]. This enables vertebrates to conserve [d] while still increasing conduction velocity. [a] [b] [c] [d] [Choose ] [Choose ] [Choose ] [Choose ]arrow_forward
- Consider a typical mammalian neuron with all of the appropriate membrane channels. If you know that neuron is at rest, at a temperature of 37°C and you know the intracellular and extracellular concentration of the potassium, which of the following statements is most likely to be true? a. The equilibrium potential of potassium would be negative if the concentration of potassium is higher on the inside. b. The equilibrium potential of potassium would be positive if the concentration of potassium is higher on the inside c. The equilibrium potential of potassium cannot be calculated because the Nernst equation requires that you know the concentration of all ions d. The equilibrium potential of potassium be zero if the concentration of potassium is higher on the outside e. None of the abovearrow_forwardPlease explain what the resting membrane potential is and its value. Make sure you include all structures involved in the creation and maintenance of the resting membrane potential. Explanation addressing the question above Membrane potential is the difference in electric potential between the interior and the exterior of a biological cell. With respect to the exterior of the cell, typical values of membrane potential range from -40 mV to -80 mV. The membrane potential has two basic functions as a battery and transmitting signals between different parts of a cell. In non-excitable cells, the membrane potential is held at a relatively stable value, called the resting potential. The resting membrane potential of a neuron is about -70 mV. At rest, there are relatively more sodium ions outside the neuron and more potassium ions inside that neuron. It is determined by concentration gradients of ions across the membrane and by membrane permeability to each type of ion. Structure and…arrow_forwardThe voltage produced by a single nerve or muscle cell is quite small, but there are many species of fish that use multiple action potentials in series to produce significant voltages. The electric organs in these fish are composed of specialized disk-shaped cells called electrocytes. The cell at rest has the usual potential difference between the inside and the outside, but the net potential difference across the cell is zero. An electrocyte is connected to nerve fibers that initially trigger a depolarization in one side of the cell but not the other. For the very short time of this depolarization, there is a net potential difference across the cell, as shown. Stacks of these cells connected in series can produce a large total voltage. Each stack can produce a small current; for more total current, more stacks are needed, connected in parallel. In an electric eel, each electrocyte can develop a voltage of 150 mV for a short time. For a total voltage of 450 V, how many electrocytes must…arrow_forward
- The figure below may help in answering some of the questions. 1. What ions are flowing (and in which direction) both during the rising phase and the falling phase of the action potential? 2. What are the values of both the 'y' (vertical) axis and the 'x' (horizontal) axis. 3. If extracellular levels of K+ rose (a condition called hyperkalemia), how would that affect the resting membrane potential? 3arrow_forwardThe giant squid axon has a diameter = 1mm and 1 = 13mm. Compared to a mammalian neuron with a diameter = 1 um and ^ = 0.2mm, which of the following is correct? graded potentials can generate action potentials in the mammalian axon but not in the squid axon. graded potential of similar magnitude would result in action potentials with larger amplitude in the mammalian axon graded potentials of similar magnitude would result in action potentials with larger amplitude in the squid axon graded potentials of similar magnitude would travel furthest from their point of origin in the mammalian axon graded potentials of similar magnitude would travel furthest from their point of origin in the squid axonarrow_forwardConotoxin is produced by marine cone snails. Among its effects is to block voltage-gated Ca2+ channels in n eurons. A. What anatomical part of a neuron would be affected by conotoxin? B. How would the neuron's action potential be affected by conotoxin? Explain, using at least TWO of the following terms: threshold, depolarization, repolarization, hyperpolarization, summation, IPSP, EPSP, exocytosis C. If conotoxin affected a somatic motor neuron, would this toxin cause muscle weakness or increased muscle tension? Explain why.arrow_forward
- An action potential is regarded as an example of positive feedback. Which of the following examples below best illustrates the positive feedback aspect of an action potential? Voltage gated potassium ion channels open slowly and remain open long enough to cause hyperpolarization The sodium potassium pump consistently moves ions as long as ATP is available, and regardless of membrane potential changes. A threshold stimulus will cause the opening of voltage gated sodium ion channels that will cause further depolarization by opening still more voltage gated sodium ion channels along the axon.arrow_forwardIn an experiment, the extracellular [Na+] surrounding a nerve cell was reduced from 145 to 45 mM. Which of the following is the most likely effect of this on action potentials? No action potentials would occur because the concentration of extracellular Na+ is too low. The membrane potential would become more negative so the threshold for action potential generation could not be reached. The nerve cell would still produce an action potential but its amplitude would be reduced and the depolarisation phase would be slower. The nerve cell would still produce an action potential but its amplitude would be reduced and the depolarization phase would be more rapid.arrow_forwardA neuron of the median giant fiber of an earthworm would respond to an increased intensity of a stimulus by: Increasing the amplitude of action potentials generated Increasing its resting membrane potential Increasing the frequency of action potentials generated Increasing the conduction velocity of action potentials generatedarrow_forward
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