To determine the reason for the position of a-amanitin to be consistent with its inhibition modes. Concept introduction: DNA or Deoxyribonucleic acid is a molecule made of two chains which coil around one another. These form a double helix which carries instructions genetical in nature like related to reproduction, growth, development, functioning of the living organisms. a-amanitin inhibits RNA polymerase II. This toxin which slows the polymerase translocation along DNA for NTP substrates has no effect on enzyme’s affinity.

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Chapter 29, Problem 17P

Interpretation Introduction

Interpretation:

To determine the reason for the position of a-amanitin to be consistent with its inhibition modes.

Concept introduction:

DNA or Deoxyribonucleic acid is a molecule made of two chains which coil around one another. These form a double helix which carries instructions genetical in nature like related to reproduction, growth, development, functioning of the living organisms.

a-amanitin inhibits RNA polymerase II. This toxin which slows the polymerase translocation along DNA for NTP substrates has no effect on enzyme’s affinity.

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