Concept explainers
(a)
To determine: The repeating amino acid residues that will result from the translation of transcripts made from repeating DNA sequences of CAG.
Introduction: The trinucleotide repeat diseases include the genetic disorders caused by an abnormal increase in the number of trinucleotide repeats in some genes. The manifestation of diseases is based on the number of repeats above the normal threshold in a gene. These may be present in the coding region or the promoter region.
(b)
To determine: The repeating amino acid residues that will result from the translation of transcripts made from repeating DNA sequences of CTG.
Introduction: The trinucleotide repeat diseases include the genetic disorders caused by an abnormal increase in the number of trinucleotide repeats in some genes. The manifestation of disease is based on the number of repeats above the normal threshold in a gene. These may be present in the coding region or the promoter region.
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