Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 28, Problem 5E

(a)

Summary Introduction

To determine: The repeating amino acid residues that will result from the translation of transcripts made from repeating DNA sequences of CAG.

Introduction: The trinucleotide repeat diseases include the genetic disorders caused by an abnormal increase in the number of trinucleotide repeats in some genes. The manifestation of diseases is based on the number of repeats above the normal threshold in a gene. These may be present in the coding region or the promoter region.

(b)

Summary Introduction

To determine: The repeating amino acid residues that will result from the translation of transcripts made from repeating DNA sequences of CTG.

Introduction: The trinucleotide repeat diseases include the genetic disorders caused by an abnormal increase in the number of trinucleotide repeats in some genes. The manifestation of disease is based on the number of repeats above the normal threshold in a gene. These may be present in the coding region or the promoter region.

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY