Biology: Concepts and Investigations
5th Edition
ISBN: 9781260259049
Author: Hoefnagels
Publisher: MCG
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 2.6, Problem 2MC
Summary Introduction
To propose:
An experiment to test the hypothesis that formic acid’s low
Concept introduction:
The
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Identify the following statements as true or false. If a statement is false, explain
what is wrong with that statement
a) Transition state analogs bind very tightly with the enzyme active site as
they form covalent bonds with the active site
b) Receptor desensitization happens upon prolonged exposure of receptors
to both agonists and antagonists
c) Dactinomycin and Doxorubicin are examples of drugs that bind with the
major groove of DNA
d) Mitomycin C forms interstrand crosslinking while cisplatin forms
intrastrand crosslinking of DNA
Explain the mechanism of glycogen hydrolysis in the presence of acid in the experiment of isolation of glycogen from chicken liver
Give typing answer with explanation and conclusion
Which of the following enzymes are inhibited by corticosteroids?
a) Lipoxygenase only
b) COX-1 only
c) COX-2 only
d) Phospholipase
Chapter 2 Solutions
Biology: Concepts and Investigations
Ch. 2.1 - Which four elements do organisms require in the...Ch. 2.1 - Where in an atom are protons, neutrons, and...Ch. 2.1 - What does an elements atomic number indicate?Ch. 2.1 - What is the relationship between the mass of 12C...Ch. 2.1 - Prob. 5MCCh. 2.2 - How are atoms, molecules, and compounds related?Ch. 2.2 - Prob. 2MCCh. 2.2 - Explain how electronegativity differences between...Ch. 2.3 - Prob. 1MCCh. 2.3 - Distinguish between a solute and a solvent and...
Ch. 2.3 - Prob. 3MCCh. 2.3 - Prob. 4MCCh. 2.3 - Prob. 5MCCh. 2.3 - Prob. 6MCCh. 2.4 - How do acids and bases affect a solution's H'...Ch. 2.4 - Prob. 2MCCh. 2.4 - How do buffers regulate the pH of a fluid?Ch. 2.5 - Prob. 1MCCh. 2.5 - Prob. 2MCCh. 2.5 - What is the significance of a protein's shape, and...Ch. 2.5 - What are some differences between RNA and DNA?Ch. 2.5 - Prob. 5MCCh. 2.5 - Prob. 6MCCh. 2.6 - Prob. 1MCCh. 2.6 - Prob. 2MCCh. 2 - Prob. 1MCQCh. 2 - Prob. 2MCQCh. 2 - Prob. 3MCQCh. 2 - Prob. 4MCQCh. 2 - Prob. 5MCQCh. 2 - Prob. 6MCQCh. 2 - The vitamin biotin contains 10 atoms of carbon, 16...Ch. 2 - Prob. 2WIOCh. 2 - Prob. 3WIOCh. 2 - Prob. 4WIOCh. 2 - Prob. 5WIOCh. 2 - Prob. 6WIOCh. 2 - Prob. 7WIOCh. 2 - Prob. 1PITCh. 2 - Prob. 2PITCh. 2 - 4. Add monomers, polymers, dehydration synthesis,...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Consider the analogy of the jiggling box containing coins that was described on page 85. The reaction, the flipping of coins that either face heads up (h) or tails up (T), is described by the equation h ↔ T, where the rate of the forward reaction equals the rate of the reverse reaction.a. What are ΔG and ΔG° in this analogy? b. What corresponds to the temperature at which the reaction proceeds? What corresponds to the activation energy of the reaction? assume you have an “enzyme,” called jigglase, which catalyzes this reaction. What would the effect of jigglase be and what, mechanically, might jigglase do in this analogy?arrow_forwardWhich of the following best explains why enzyme catalysis is affected by a change in pH? A. Change in pH alters ionization states of serine in the active site involved in nucleophilic catalysis B. The ionization states of his, asp and glu involved in acid/base catalysis are altered with change in pH C. Change in pH alters ionization states of contact amino acids in the active site D. All enzymes have optimum pHarrow_forwardThe authors in the abstract given above describe the mechanism for the activation of metallothionein (MTF) that results in the detoxification of heavy metals. Use a diagram to illustrate and describe the cascade of events that occur as proposed by the authors.arrow_forward
- The authors in the abstract given above describe the mechanism for the activation of metallothionein (MTF) that results in the detoxification of heavy metals. Use a diagram to illustrate and describe the cascade of events that occur as proposed by the authors. Induction of metallothionein (MT) expression is involved in metal homeostasis and detoxification. To identify the key pathways that regulate metal-induced cytotoxicity, we investigate how phosphorylated metal-responsive transcription factor-1 (MTF-1) contributed to induction of MT expression. Immortal human embryonic kidney cells (HEK cells) were treated with seven kinds of metals including cadmium chloride (CdCl2), zinc sulphate (ZnSO4), copper sulphate (CuSO4), lead acetate (PbAc), nickel sulphate (NiSO4), sodium arsenite (NaAsO2), and potassium bichromate (K2Cr2O7). The MT expression was induced in a dose-response and time-dependent manner upon various metal treatments. A cycle of phosphorylation and dephosphorylation was…arrow_forwardThe following diagram shows the biosynthesis of B12 coenzymes, starting with the vitamin. DMB is dimethylbenzimidazole. (a) What one additional substrate or cofactor is required by enzyme B?(b) Genetic deficiency in animals of enzyme C would result in excessiveurinary excretion of what compound?(c) Some forms of the condition described in (b) can be successfully treatedby injection of rather massive doses of vitamin B12. What kind ofgenetic alteration in the enzyme would be consistent with this result?(d) Genetic deficiency in animals of enzyme B will result in excessive urinaryexcretion of what amino acid?arrow_forwardAn experiment was carried out to measure the reaction rate of hydrolysis of acetylcholme (substrate) with serum enzymes (Eadie, 1949). In the experiment, two experiments were conducted, namely experiment 1 without using a prostigmine inhibitor and experiment 2 using a prostigmine inhibitor at 1.5 x 10^-7 mol/l. the data obtained are: a. Is prostigmine competitive or noncompetitive inhibitor? b. determine the value of km and rmax for the two experiments, comparearrow_forward
- . Based on what you know about enzyme inhibition, classify the following examples as irreversible, competitive, or noncompetitive enzyme inhibition. A) competitive B) noncompetitive C) irreversible 1) Diisopropyl fluorophosphate binds to acetylcholinesterase and permanently inactivates the enzyme. Paralysis results. 2) A drug binds to the active site of an enzyme but disassociates and leaves the enzyme active. 3) A toxin binds to the surface of an enzyme. The enzyme then binds the substrate, but no product is produced. The toxin may disassociate and the enzyme will become active again. 4) Vitamin K is a coenzyme involved in blood clotting. An anticoagulant drug binds at the site of vitamin K bonding, blocking vitamin K binding and preventing clotting. Clotting resumes after the patient stops taking the drug. 5) Aspirin binds to prostaglandin synthetase and permanently stops its ability to produce prostaglandin.arrow_forwardUse the data from the table below to answer the questions on an ezyme obtained from potato extract. The greater the absorbance value, the more product generated for each chemical reaction Table 1: Summary Data for Enzyme Catalyzed Reaction Product Formation Measured as Absorbance Tube Distilled Water Catechol PTU (Inhibitor) Potato Extract Results (Absorbance) 1 5.5 ml 0.5 ml -- --- 0.02 2 5 ml 0.5 ml --- 0.5 ml 0.68 3 4.5 ml 0.5 ml 0.5 ml 0.5 ml 0.04 4 4.5 ml 0.5 ml 1.0 ml 1.26 5 4.5 ml 1.0 ml 0.5 ml 1.22 a) Explain with respect to enzyme activity why test tube 1 produced very little absorbance: b) Explain with respect to enzyme activity why test tube 3 produced very little absorbance: c) Explain how to tubes 4 and 5 differ with respect to reaction conditions. d) Explain with respect to enzyme activity why tubes 4 and 5 have similar absorbance and why both have…arrow_forwardConsider a reaction in which reactants X and Y combine to form the product Z. The diagram below compares the reaction coordinates for the catalyzed and uncatalyzed pathways of this reaction. B. X+Y Reaction Coordinate What does letter B represent? O Letter B represents the activation energy of the uncatalyzed reaction pathway. Letter B represents the energy difference between the reactants and products for the uncatalyzed pathway. O Letter B represents the activation energy of the catalyzed reaction pathway. Letter B represents the energy difference between the reactants and products for the catalyzed pathway. Energyarrow_forward
- Write out a complete mechanism for the conversion of serine into aminoacrylate catalyzed by serine dehydratase.arrow_forwardFor each of the following examples, indicate whether the drug is acting on physical process, chemical process or enzymatic system (your answer should be only; Physical, Chemical or Enzymatic). A. A drug is used as an antidote in lead poisoning and acts by binding to lead particles in body (chelation therapy). B. A drug acts to reduce flatulence and acts by reducing the surface tension of intestinal gas bubbles in the GI tract (e.g. Simethicone). C. A drug competes with alpha-glucosidase in intestine to reduce glucose conversion from disaccharides (e.g. Acarbose).arrow_forwardDescribe the two models that explain the binding of allosteric enzymes. Use either model to explain the binding ofoxygen to hemoglobin.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education