Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Chapter 23.4, Problem 1CS
Summary Introduction
To determine: The three different genetic changes that one would expect to be neutral with reference to the genetic code described in table 12.1 given in the text book.
Introduction: The genetic code can be defined as a particular set of rules that is used by the living organisms for translating the given information encoded within the sequences of genetic material into the functional proteins.
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Bioinformatics:
Explore the applications of bioinformatics in genomics research. How do computational methods contribute to understanding genetic variations and their implications for personalized medicine?
Objective: Get a sense of how genomics, the study of the genome in its entirety,needs to think about how to go about its research.
Geonomic DNA is broken up into fragments. The 5’ and 3’ ends of each fragment(a “read”) are sequenced. The sequenced reads are assembled together intocontiguous sequences (“contigs”) based on sequence similarity.
The idea is to sequence enough random fragments so that every nucleotide in thegenome is represented on some read. The number of such fragments needed iscalled the coverage, c.
The coverage c can be calculated by the formula RL/G, where R is the number ofreads sequenced, L is the average length of a read and G is the total length of thegenome. The units of length are bases (b) or base pairs (bp).
Consider a genome whose length is 1000 bp. “Shotgun” sequencing techniquesare applied to the genome, resulting in 20 reads, with an average length of 50 bp.A very important point is that, even though 20 x 50 = 1000, there is no guaranteethat ALL…
Objective: Get a sense of how genomics, the study of the genome in its entirety,needs to think about how to go about its research.
Geonomic DNA is broken up into fragments. The 5’ and 3’ ends of each fragment(a “read”) are sequenced. The sequenced reads are assembled together intocontiguous sequences (“contigs”) based on sequence similarity.
The idea is to sequence enough random fragments so that every nucleotide in thegenome is represented on some read. The number of such fragments needed iscalled the coverage, c.
The coverage c can be calculated by the formula RL/G, where R is the number ofreads sequenced, L is the average length of a read and G is the total length of thegenome. The units of length are bases (b) or base pairs (bp).
Consider a genome whose length is 1000 bp. “Shotgun” sequencing techniquesare applied to the genome, resulting in 20 reads, with an average length of 50 bp.A very important point is that, even though 20 x 50 = 1000, there is no guaranteethat ALL…
Chapter 23 Solutions
Biology
Ch. 23.1 - Prob. 1CSCh. 23.2 - Prob. 1CCCh. 23.2 - Prob. 2CCCh. 23.2 - Prob. 3CCCh. 23.3 - Prob. 1CCCh. 23.3 - Prob. 1EQCh. 23.3 - Prob. 2EQCh. 23.3 - Prob. 3EQCh. 23.4 - Genetic Drift Concept Check: How does the...Ch. 23.4 - Prob. 1CS
Ch. 23.5 - Prob. 1CCCh. 23 - Population geneticists are interested in the...Ch. 23 - The Hardy-Weinberg equation characterizes the...Ch. 23 - Prob. 3TYCh. 23 - Prob. 4TYCh. 23 - Prob. 5TYCh. 23 - Prob. 6TYCh. 23 - Prob. 7TYCh. 23 - Prob. 8TYCh. 23 - Kimuras proposal regarding neutral variation...Ch. 23 - Populations that experience inbreeding may also...Ch. 23 - Prob. 1CQCh. 23 - Prob. 2CQCh. 23 - Prob. 3CQCh. 23 - Antibiotics are commonly used to combat bacterial...Ch. 23 - Discuss die similarities and differences among...
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