Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
16th Edition
ISBN: 9781260231700
Author: Sylvia S. Mader, Michael Windelspecht
Publisher: McGraw Hill Education
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Chapter 23.3, Problem 1QTC

What would be the potential consequences if one of the genes involved in a multiple gene interaction were to develop an error?

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Two methods for functionally inactivating a gene without altering the gene sequence involve dominant negative alleles and RNA interference (RNAi). Describe how each method can inhibit expression of a gene.
Which of the following conditions is most likely to be successfully treated by gene therapy using a viral vector to deliver a wild-type copy of one gene that is present in mutant form in a person with the condition? Assume that the viral vector used has the ability to home to relevant target tissues. Also assume that the patient can be treated at a young enough age to avoid irreversible phenotypic impacts of the mutation described. Timothy Syndrome, a multi-system disorder characterized by dysmorphic features and autistic behavioral traits, caused by overexpression of calcium channel gene Cerebral adrenoleukodystrophy (ALD), a neurological disorder caused by a frameshift mutation knocking out the function of the ABCD1 gene encoding a lipid transporter Osteogenesis imperfecta caused by a dominant negative mutation in the collagen A1 gene Myopia (shortsightedness), a vision impairment with heritability estimates in the range of 0.6-0.8, where risk is impacted by at least 200 genes
Cap, EA1, and Sap are all genes/proteins of interest in this study. For each gene, what gene product is encoded and where is the gene (the literal DNA sequence) located physically in the cell?    I need help fimiding this in the artticle and answer as short as possible  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106848/

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Inquiry Into Life (16th Edition)

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