Introduction to General, Organic and Biochemistry
11th Edition
ISBN: 9781285869759
Author: Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher: Cengage Learning
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Chapter 23, Problem 23.49P
Interpretation Introduction
Interpretation:
An explanation corresponding to the statement that transition-state analogs relate to the idea of the induced-fit model of enzymes is to be stated.
Concept Introduction:
Transition state analogs consist of similar shape of the transition state of substrate. An enzyme catalyzes a reaction and makes the transition state more stable by lowering the activation energy. A molecule behaves as an inhibitor of an enzyme when it imitates the transition state of a
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Chapter 23 Solutions
Introduction to General, Organic and Biochemistry
Ch. 23 - What is the difference between a catalyst and an...Ch. 23 - What are ribozymes made of?Ch. 23 - Would a lipase hydrolyze two triglycerides, one...Ch. 23 - Compare the activation energy in uncatalyzed...Ch. 23 - Prob. 23.5PCh. 23 - Prob. 23.6PCh. 23 - Prob. 23.7PCh. 23 - Monoamine oxidases are important enzymes in brain...Ch. 23 - Prob. 23.9PCh. 23 - 0 What kind of reaction does each of the following...
Ch. 23 - Prob. 23.11PCh. 23 - Prob. 23.12PCh. 23 - 3 What is the difference between reversible and...Ch. 23 - Prob. 23.14PCh. 23 - 5 At a very low concentration of a certain...Ch. 23 - 6 If we wish to double the rate of an...Ch. 23 - 7 A bacterial enzyme has the following...Ch. 23 - 8 The optimal temperature for the action of...Ch. 23 - 9 The activity of pepsin was measured at various...Ch. 23 - Prob. 23.20PCh. 23 - Prob. 23.21PCh. 23 - Prob. 23.22PCh. 23 - Prob. 23.23PCh. 23 - 4 What kind of chemical reaction occurs most...Ch. 23 - 5 Which of the following is a correct statement...Ch. 23 - Prob. 23.26PCh. 23 - 7 Enzymes are long protein chains, usually...Ch. 23 - Prob. 23.28PCh. 23 - Prob. 23.29PCh. 23 - 0 Can the product of a reaction that is part of a...Ch. 23 - 1 What is the difference between a zymogen and a...Ch. 23 - 2 The enzyme trypsin is synthesized by the body in...Ch. 23 - Prob. 23.33PCh. 23 - Prob. 23.34PCh. 23 - Prob. 23.35PCh. 23 - Prob. 23.36PCh. 23 - Prob. 23.37PCh. 23 - Prob. 23.38PCh. 23 - 9 The enzyme phosphofructokinase (PFK) (Chapter...Ch. 23 - Prob. 23.40PCh. 23 - 1 After a heart attack, the levels of certain...Ch. 23 - Prob. 23.42PCh. 23 - Prob. 23.43PCh. 23 - Prob. 23.44PCh. 23 - 5 Chemists who have been exposed for years to or...Ch. 23 - 6 Which enzyme preparation is given to patients...Ch. 23 - 7 Chymotrypsm is secreted by the pancreas and...Ch. 23 - 8 Explain why transition-state analogs are potent...Ch. 23 - Prob. 23.49PCh. 23 - 0 Explain the relationship between...Ch. 23 - 1 (Chemical Connections 23A) Acetylcholine causes...Ch. 23 - Prob. 23.52PCh. 23 - Prob. 23.53PCh. 23 - Prob. 23.54PCh. 23 - Prob. 23.55PCh. 23 - 6 (Chemical Connections 23C) What role does Mn2+...Ch. 23 - 7 (Chemical Connections 23C) Which amino acids of...Ch. 23 - 8 (Chemical Connections 23D) What is the strategy...Ch. 23 - 9 (Chemical Connections 23D) Why did scientists...Ch. 23 - Prob. 23.60PCh. 23 - Prob. 23.61PCh. 23 - Prob. 23.62PCh. 23 - 3 (Chemical Connections 23E) What is the...Ch. 23 - Prob. 23.64PCh. 23 - Prob. 23.65PCh. 23 - Prob. 23.66PCh. 23 - Prob. 23.67PCh. 23 - Prob. 23.68PCh. 23 - Prob. 23.69PCh. 23 - Prob. 23.70PCh. 23 - 1 Food can be preserved by inactivation of enzymes...Ch. 23 - Prob. 23.72PCh. 23 - 3 Would you expect to find active digestive...Ch. 23 - Prob. 23.74PCh. 23 - Prob. 23.75PCh. 23 - Prob. 23.76PCh. 23 - 7 An enzyme has the following pH dependence: At...Ch. 23 - Prob. 23.78PCh. 23 - Prob. 23.79PCh. 23 - 0 Nerve gases operate by forming covalent bonds at...Ch. 23 - 1 What would be the appropriate name for an enzyme...Ch. 23 - Prob. 23.82PCh. 23 - 3 A liver enzyme is made of four subunits: 2A and...Ch. 23 - Prob. 23.84PCh. 23 - Prob. 23.85PCh. 23 - Prob. 23.86PCh. 23 - Prob. 23.87PCh. 23 - Prob. 23.88PCh. 23 - Prob. 23.89PCh. 23 - Prob. 23.90PCh. 23 - Prob. 23.91P
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Similar questions
- Why are enzymes important? For example, what is the importance of the enzyme carbonic anhydrase in the body?arrow_forwardMost human enzymes function best in the temperature range of: a. 0C10C b. 10C25C c. 25C40C d. 40C55Carrow_forwardCompare the lock-and-key and induced-fit models for substrate binding to an enzyme.arrow_forward
- Describe the difference between graphs showing temperature versus reaction rate for an enzyme-catalyzed reaction and an uncatalyzed reaction.arrow_forwardWhy are enzymes that are used for laboratory or clinical work stored in refrigerators?arrow_forwardThe site on an enzyme molecule that does the catalytic work is called the: a. binding site. b. allosteric site. c. lock. d. active site.arrow_forward
- . Describe the lock-and-key model for enzymes. Why are the shapes of the enzyme and its substrate important in this model? What does it mean to say that an enzyme is inhibited by a particular molecule? What happens if this inhibition is irreversible? Can you think of a situation in which it might be advantageous to be able to inhibit an enzyme?arrow_forwardEnzymes catalysts that increase the rates of biochemical reactions. are True Falsearrow_forward84°F Partly sunny Only the substrate molecule for a particular enzyme will fit into the active site. This is known as the lock-and-key mechanism. What does that say about the relationship between the enzyme and the substrate? O The enzyme will catalyze two chemical reactions with one substrate. The enzyme will catalyze all chemicals with one substrate. O The enzyme will not catalyze any chemicals with any substrates. O The enzyme will catalyze only one chemical with only one substrate. الی کی E $ R F CV 5 T O Search FO G B ^ Y H F8 & 7 N 8 ľ M a ( 9 K O 0 L P - + 4) O 10:28 6/12/20arrow_forward
- Enzymes take part in nearly all metabolic reactions. What is an enzyme's impact on the activation energy of a chemical reaction? There are two parts. How do enzymes affect the activation energy of a reaction? Label the reaction energy diagram with the appropriate terms. Effect of enzymes Answer Bank activation energy with enzyme activation energy without enzyme Course of reaction Energyarrow_forward4. D) True or False: In order for a catalyst to function, it must exist in the same phase as the substrate.arrow_forwardGiven Enzymes: amylase, lipase, lactasearrow_forward
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Enzyme Catalysis Part-I; Author: NPTEL-NOC IITM;https://www.youtube.com/watch?v=aZE740JWZuQ;License: Standard Youtube License