Concept explainers
(a)
Interpretation:
The major product of the given crossed Claisen condensation has to be stated.
Concept introduction:
In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.
(b)
Interpretation:
The major product of the given crossed Claisen condensation is to be stated.
Concept introduction:
In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.
(c)
Interpretation:
The major product of the given crossed Claisen condensation is to be stated.
Concept introduction:
In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.
Want to see the full answer?
Check out a sample textbook solutionChapter 22 Solutions
ORGANIC CHEMISTRY MASTERINGCHEM ACCESS
- Organic Chemistry What is the major product of the following reaction sequence?arrow_forwardPredict the major product of the following reactions. If it is possible, write all stereoisomers.arrow_forwardPredict the major product of the following reactions. The formulae of the products are given in bold.arrow_forward
- 2) Predict the products of the following Claisen condensations. LOCH3 CH,O CH,OHarrow_forwardPredict the products of Claisen and crossed Claisen condensations, and proposemechanisms. Show how a Claisen condensation constructs the carbon skeleton of atarget moleculearrow_forwardWhat is the major product of the following reaction? With explanation please!arrow_forward