Anatomy and Physiology
Anatomy and Physiology
9th Edition
ISBN: 9781260256000
Author: SALADIN
Publisher: MCG
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Chapter 21, Problem 4TYC

A burn research center uses mice for studies of skin grafting. To prevent graft rejection, the mice are thymectomized at birth. Even though B cells do not develop in the thymus, these mice show no humoral immune response and are very susceptible to infection. Explain why the removal of the thymus would improve the success of skin grafts but adversely affect humoral immunity.

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New Skin' research center uses mice for studies of skin grafting. To prevent rejection of the graft, the mice are thymectomized (taking out thymus) at birth. Even though B cells do not develop in the thymus, these mice show no humoral immune response and are very susceptible to infection. Explain why the removal of the thymus would improve the success of skin grafts but adversely affect humoral immunity.
In studies of skin grafts, thymectomized mice (their thymus has been removed) are often used. B cells don’t develop in the thymus, but nonetheless, these mice are often subject to infection.  Why would the removal of the thymus improve the success of skin grafts, but adversely affect immunity?
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Chapter 21 Solutions

Anatomy and Physiology

Ch. 21.1 - Prob. 6AYLOCh. 21.1 - Prob. 7AYLOCh. 21.1 - The nature of diffuse lymphatic tissue and where...Ch. 21.1 - Prob. 9AYLOCh. 21.1 - Prob. 10AYLOCh. 21.1 - Prob. 11AYLOCh. 21.1 - Prob. 12AYLOCh. 21.1 - Prob. 13AYLOCh. 21.1 - Prob. 14AYLOCh. 21.1 - Location, gross anatomy, and histology of the...Ch. 21.2 - Prob. 6BYGOCh. 21.2 - Prob. 7BYGOCh. 21.2 - How do interferons and the complement system...Ch. 21.2 - Prob. 9BYGOCh. 21.2 - List the cardinal signs of inflammation and state...Ch. 21.2 - Prob. 1AYLOCh. 21.2 - Prob. 2AYLOCh. 21.2 - Differences between innate and adaptive immunity;...Ch. 21.2 - Prob. 4AYLOCh. 21.2 - Prob. 5AYLOCh. 21.2 - Prob. 6AYLOCh. 21.2 - The one type of lymphocyte that is involved in...Ch. 21.2 - Types of macrophages; their origin and functionsCh. 21.2 - Prob. 9AYLOCh. 21.2 - Prob. 10AYLOCh. 21.2 - Prob. 11AYLOCh. 21.2 - Prob. 12AYLOCh. 21.2 - Prob. 13AYLOCh. 21.2 - Prob. 14AYLOCh. 21.2 - Prob. 15AYLOCh. 21.2 - Prob. 16AYLOCh. 21.2 - Examples of inflammatory cytokines and their rolesCh. 21.2 - How hyperemia, bradykinin, and other factors...Ch. 21.2 - Prob. 19AYLOCh. 21.2 - Prob. 20AYLOCh. 21.2 - Prob. 21AYLOCh. 21.3 - Prob. 11BYGOCh. 21.3 - Prob. 12BYGOCh. 21.3 - Contrast active and passive immunity. Give natural...Ch. 21.3 - Prob. 14BYGOCh. 21.3 - Prob. 15BYGOCh. 21.3 - Prob. 16BYGOCh. 21.3 - Prob. 17BYGOCh. 21.3 - Prob. 18BYGOCh. 21.3 - Prob. 1AYLOCh. 21.3 - Prob. 2AYLOCh. 21.3 - How adaptive immunity is classified as active or...Ch. 21.3 - Prob. 4AYLOCh. 21.3 - Prob. 5AYLOCh. 21.3 - Prob. 6AYLOCh. 21.3 - Prob. 7AYLOCh. 21.3 - Prob. 8AYLOCh. 21.3 - Prob. 9AYLOCh. 21.3 - Prob. 10AYLOCh. 21.3 - The meanings of immunocompetence and...Ch. 21.3 - Prob. 12AYLOCh. 21.3 - Prob. 13AYLOCh. 21.3 - Prob. 14AYLOCh. 21.4 - Prob. 19BYGOCh. 21.4 - Prob. 20BYGOCh. 21.4 - Prob. 21BYGOCh. 21.4 - Prob. 22BYGOCh. 21.4 - Prob. 1AYLOCh. 21.4 - Prob. 2AYLOCh. 21.4 - Prob. 3AYLOCh. 21.4 - Prob. 4AYLOCh. 21.4 - Prob. 5AYLOCh. 21.4 - How activated Tc cells destroy target cells; the...Ch. 21.4 - Prob. 7AYLOCh. 21.5 - Prob. 23BYGOCh. 21.5 - Prob. 24BYGOCh. 21.5 - Prob. 25BYGOCh. 21.5 - Similarities and differences between humoral and...Ch. 21.5 - Prob. 2AYLOCh. 21.5 - Prob. 3AYLOCh. 21.5 - Prob. 4AYLOCh. 21.5 - Prob. 5AYLOCh. 21.6 - Prob. 26BYGOCh. 21.6 - Prob. 27BYGOCh. 21.6 - Prob. 28BYGOCh. 21.6 - Prob. 29BYGOCh. 21.6 - Prob. 30BYGOCh. 21.6 - Prob. 1AYLOCh. 21.6 - Prob. 2AYLOCh. 21.6 - Prob. 3AYLOCh. 21.6 - Prob. 4AYLOCh. 21.6 - The pathology of acquired immunodeficiency...Ch. 21 - The only lymphatic organ with both afferent and...Ch. 21 - Prob. 2TYRCh. 21 - Prob. 3TYRCh. 21 - Which of these is a macrophage? a. a microglial...Ch. 21 - Prob. 5TYRCh. 21 - Prob. 6TYRCh. 21 - Which of the following correctly stales the order...Ch. 21 - Prob. 8TYRCh. 21 - Prob. 9TYRCh. 21 - Which of the following results from a lack of...Ch. 21 - Any microorganism capable of causing disease is...Ch. 21 - Prob. 12TYRCh. 21 - Prob. 13TYRCh. 21 - Prob. 14TYRCh. 21 - Prob. 15TYRCh. 21 - Prob. 16TYRCh. 21 - Prob. 17TYRCh. 21 - Prob. 18TYRCh. 21 - Prob. 19TYRCh. 21 - Prob. 20TYRCh. 21 - Prob. 1BYMVCh. 21 - crino-Ch. 21 - extra-Ch. 21 - Prob. 4BYMVCh. 21 - Prob. 5BYMVCh. 21 - Prob. 6BYMVCh. 21 - Prob. 7BYMVCh. 21 - Prob. 8BYMVCh. 21 - Prob. 9BYMVCh. 21 - Prob. 10BYMVCh. 21 - Prob. 1WWTSCh. 21 - Prob. 2WWTSCh. 21 - Prob. 3WWTSCh. 21 - Prob. 4WWTSCh. 21 - Prob. 5WWTSCh. 21 - Prob. 6WWTSCh. 21 - Prob. 7WWTSCh. 21 - Prob. 8WWTSCh. 21 - Prob. 9WWTSCh. 21 - B cells that circulate freely in the bloodstream...Ch. 21 - Prob. 1TYCCh. 21 - Prob. 2TYCCh. 21 - A girl with a defective heart receives a new heart...Ch. 21 - A burn research center uses mice for studies of...Ch. 21 - Prob. 5TYC
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