Microbiology: An Introduction (13th Edition)
Microbiology: An Introduction (13th Edition)
13th Edition
ISBN: 9780134605180
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case, Derek Weber, Warner Bair
Publisher: PEARSON
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Chapter 21, Problem 10R
Summary Introduction

To review:

An anaerobic gram positive bacillus found on the skin. This bacterium causes skin infections which are often treated with retinoid or benzoyl peroxide.

Introduction:

Propionibacterium acnesis a gram positive anaerobic rod shaped bacterium which is the common cause of acne. Some of the other infections caused by this bacterium include blepharitis and endophthalmitis.

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Propionibacterium acnes is a normal member of the skin microbiome that benefits the body by lowering the skin's pH- an antimicrobial effect. However, P. acnes is also the leading cause of acne. Explain mechanistically how can a bacterium be normal and beneficial but also be pathogenic?
A 55-year-old woman with type 2 diabetes mellitus comes to the physician with a 2-day history of oozing, foul-smelling wound on her foot. Physical examination shows a 4-cm, necrotizing wound on the heel with purplish black discoloration of the skin around the wound, and crepitant bullae producing thin, serous fluid. A Gram stain of tissue biopsy from the site shows gram-positive rods. Which of the following toxins is produced by the most likely causal organism? Answers A-E Alpha toxin B Endotoxin C Exfoliative toxin D Exotoxin A E Panton Valentine toxin 45 QUESTIONS VERSION 2M64 MacBook Pro Notes Previous Comments Next
Intense fever, shock, and other symptoms occur in some gram-positive bacterial infections due to:   superantigens Genotoxins membrane-disrupting toxins
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