Campbell Biology (11th Edition)
11th Edition
ISBN: 9780134093413
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Textbook Question
Chapter 20, Problem 5TYU
DNA technology has many medical applications. Which of the following is not done routinely at present?
(A) production of hormones for treating diabetes and dwarfism
(B) analysis of gene expression for more informed cancer treatments
(c) gene editing by the CRISPR-Cas9 system in viable human embryos to correct genetic diseases
(D) prenatal identification of genetic disease alleles
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pick a specific disease that is currently a candidate for gene therapy—(a)briefly describing the gene mutation(s) and resulting disease symptoms, (b)brief description of a current gene therapy approach(es) for this disease. Has this approach shown any potential successes in disease treatment?
Genome annotation refers to ...
1.) lining up overlapping regions in short shotgun sequencing reads to assemble
larger contiguous DNA sequences (contigs/scaffolds).
2.) using long-read sequencing platforms (such as PacBio or Oxford Nanopore) to gather information about the epigenetic status of each region of a sequenced genome.
3.) the process of predicting which parts of a genome sequence code for functional products (such as protein-coding genes), what those products do, and assigning them names.
4.) sequencing messengeRNA measure the relative expression levels of genes in
one or more tissue samples.
the most efficient general strategy for whole genome sequencing is ?
(a) double the coding sequence after sequencing the proteins
(b) shotgun sequence and assemble based on overlaps
(c) identify mutations that affect glycolysis
(d) obtain recombinant DNA clone maps before starting the sequencing
(e) obtain comprehensive SNP maps before determining the order of DNA clone
Chapter 20 Solutions
Campbell Biology (11th Edition)
Ch. 20.1 - Prob. 1CCCh. 20.1 - DRAW IT One Strand of a DNA molecule has the...Ch. 20.1 - What are some potential difficulties in using...Ch. 20.1 - VISUAL SKILLS Compare Figure 20.7 with Figure...Ch. 20.2 - Prob. 1CCCh. 20.2 - Prob. 2CCCh. 20.3 - Based on current knowledge, how would you explain...Ch. 20.3 - Prob. 2CCCh. 20.3 - Prob. 3CCCh. 20.4 - What is the advantage of using stem cells for gene...
Ch. 20.4 - Prob. 2CCCh. 20.4 - Prob. 3CCCh. 20 - Describe how the process of gene doning results in...Ch. 20 - What useful Information is obtained by detecting...Ch. 20 - Describe how, using mice. a researcher could carry...Ch. 20 - What factors affecf whether a given genetic...Ch. 20 - In DNA technology, the term vector can refer to...Ch. 20 - Which of the following tools of DNA technology is...Ch. 20 - Prob. 3TYUCh. 20 - A paleontologist has recovered a bit of tissue...Ch. 20 - DNA technology has many medical applications....Ch. 20 - Which of the following is not true of cDNA...Ch. 20 - Expression of a cloned eukaryotic gene in a...Ch. 20 - Which Ii of the following sequences in...Ch. 20 - Prob. 9TYUCh. 20 - MAKE CONNECTIONS Looking at Figure 20.15, what...Ch. 20 - DRAW IT You are cloning an aardvark gene, using a...Ch. 20 - EVOLUTlON CONNECTION Ethical considerations aside,...Ch. 20 - Prob. 13TYUCh. 20 - Prob. 14TYUCh. 20 - The water in the Yellowstone National Park hot...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Fill in the gaps? One major goal/motivation in the development of synthetic genomes is ...... . Another branch of SB aims implementing ......... using biological building blocks is called ....... .arrow_forwardPluripotent stem cells (a) lose genetic material during development (b) give rise to many, but not all, types of cells in an organism (c) organize into recognizable structures through pattern formation (d) cannot grow in tissue culture (e) have been used to clone a sheep and several other mammalsarrow_forwardGENETICS if/when a "whole-genome shotgun" approach is used for DNA sequencing, which of the following is MOST likely to create problems during the assembly of a complete genomic sequence? a) long sequence reads b) a high degree of coverage/ redundancy in the sequence data c) the presence of repetitive DNA d) not enough contigs e) all of the abovearrow_forward
- A number of advances have been made in biotechnology. CRISPR/Cas9 one of the most controversial, and has had a lot of media attention in recent years. It is a method by which scientists can precisely edit DNA sequences at exact locations. Benefits obviously include the potential to “repair” mutated genes that cause disease. In fact, preliminary results from one of the earliest clinical trials of CRISPR/Cas9 provide evidence that the technique is safe and feasible to use for treating human diseases. What other potential applications of this application do you see (you can use any organisms to illustrate your answer)? What are the potential dangers or downsides of using this technology? Do you think this technology should be used in gene editing in humans? Explain your stance.arrow_forwardBioinformatics includes all of the following except (A) using computer programs to align DNA sequences. (B) using DNA technology to combine DNA from two different sources in a test tube. (C) developing computer-based tools for genome analysis. (D) using mathematical tools to make sense of biological systems.arrow_forwardAlthough it is well known that X-rays cause mutations, they are routinely used to diagnose medical problems, including potential tumors, broken bones, and dental cavities. Why is this done? What precautions need to be taken?arrow_forward
- Because genetic engineering involves the modification of an organism's set of instructions, it has created a dilemma raising both moral and ethical concerns. For instance, a biotechnological company has found a way to produce rice that is immune to pests and diseases, which is vital for the establishment of food security. However, the methods that will be implemented are by splicing off the genes of endangered pandas using invasive procedures that may harm their population. Will you support this? Why or why not? Limit your answers to 5 sentences or less. Be brief and concise.arrow_forwardhttps://www.khanacademy.org/science/biology/biotech-dna-technology/dna-cloning-tutorial/a/overview-dna-cloning That is the link for the example ^arrow_forwardYou just graduated from college and started working at a biotech startup called Scrofabulous. Your first job assignment is to clone the pig gene for the hormone prolactin. Assume that the pig gene for prolactin has not yet been isolated, sequenced, or mapped; What would be the most useful and economical first step to go about identifying and cloning the pig gene for prolactin? use the amino acid sequence of mouse prolactin to design a pair of degenerate oligonucleotide PCR primers to PCR-amplify the pig prolactin gene. RNAseq the pituitary gland of the pig, the most abundant gene is likely to to be prolactin Conduct a proteome search for peptides that match parts of mouse prolactin protein Sequence the pig genome, then translate the genome to find the gene predicted to encode for prolactin Crystalize the mouse prolactin protein and use Google's DeepMind Al to find the closest amino acid sequence in the pig proteomearrow_forward
- Do not use chatgpt.arrow_forwardBiotechnology is a constantly developing field with many exciting applications. It focuses on the use of living organisms and their biological processes to make useful products and address practical problems. This includes advancements in clinical diagnostics, epidemiological tracking, forensics, industry, and many other areas. In this simulation, you will have the opportunity to perform molecular techniques commonly used in the field of biotechnology to create medically important compounds such as insulin and human growth hormone.Bacteria can obtain naked DNA from their environment in a process called transformation. This process occurs naturally but can also be used in the genetic engineering field to alter the genetic makeup of bacteria. In this simulation, you transform bacteria with a jellyfish gene whose product is green fluorescent protein. The transformed bacteria now have the genetic information to produce GFP (green fluorescent protein), causing them to glow green under…arrow_forwardBriefly compare (a) restriction enzymes, (b) engineered nucleases and (c) CRISPR-Cas in terms of their origin, nature, and mechanism.arrow_forward
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