Campbell Biology (11th Edition)
11th Edition
ISBN: 9780134093413
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Textbook Question
Chapter 20, Problem 5TYU
DNA technology has many medical applications. Which of the following is not done routinely at present?
(A) production of hormones for treating diabetes and dwarfism
(B) analysis of gene expression for more informed cancer treatments
(c) gene editing by the CRISPR-Cas9 system in viable human embryos to correct genetic diseases
(D) prenatal identification of genetic disease alleles
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pick a specific disease that is currently a candidate for gene therapy—(a)briefly describing the gene mutation(s) and resulting disease symptoms, (b)brief description of a current gene therapy approach(es) for this disease. Has this approach shown any potential successes in disease treatment?
A friend of yours who works at a biotechnology start up company has computationally designed three new proteins that she thinks might be able to prevent and possibly reverse cancers if they could be expressed/transported in the right location in human cells. If this works, the company will be worth billions and everyone who works there will be rich. Not to mention curing cancer…
The plan is to use a genetically modified, harmless virus to deliver the DNA genes for these three proteins. This should result in the transcription of mRNA and translation of the three proteins. The trick is getting the proteins to go to the right places in the cells so they can interact with the right cellular pathways.
The first protein is a transcription factor that binds to DNA and should shut down transcription of cancer promoting genes by binding to their promoters. The second is a protein that interacts with electron transport chain proteins to reduce the output of reactive free radicals in…
Genome annotation refers to ...
1.) lining up overlapping regions in short shotgun sequencing reads to assemble
larger contiguous DNA sequences (contigs/scaffolds).
2.) using long-read sequencing platforms (such as PacBio or Oxford Nanopore) to gather information about the epigenetic status of each region of a sequenced genome.
3.) the process of predicting which parts of a genome sequence code for functional products (such as protein-coding genes), what those products do, and assigning them names.
4.) sequencing messengeRNA measure the relative expression levels of genes in
one or more tissue samples.
Chapter 20 Solutions
Campbell Biology (11th Edition)
Ch. 20.1 - Prob. 1CCCh. 20.1 - DRAW IT One Strand of a DNA molecule has the...Ch. 20.1 - What are some potential difficulties in using...Ch. 20.1 - VISUAL SKILLS Compare Figure 20.7 with Figure...Ch. 20.2 - Prob. 1CCCh. 20.2 - Prob. 2CCCh. 20.3 - Based on current knowledge, how would you explain...Ch. 20.3 - Prob. 2CCCh. 20.3 - Prob. 3CCCh. 20.4 - What is the advantage of using stem cells for gene...
Ch. 20.4 - Prob. 2CCCh. 20.4 - Prob. 3CCCh. 20 - Describe how the process of gene doning results in...Ch. 20 - What useful Information is obtained by detecting...Ch. 20 - Describe how, using mice. a researcher could carry...Ch. 20 - What factors affecf whether a given genetic...Ch. 20 - In DNA technology, the term vector can refer to...Ch. 20 - Which of the following tools of DNA technology is...Ch. 20 - Prob. 3TYUCh. 20 - A paleontologist has recovered a bit of tissue...Ch. 20 - DNA technology has many medical applications....Ch. 20 - Which of the following is not true of cDNA...Ch. 20 - Expression of a cloned eukaryotic gene in a...Ch. 20 - Which Ii of the following sequences in...Ch. 20 - Prob. 9TYUCh. 20 - MAKE CONNECTIONS Looking at Figure 20.15, what...Ch. 20 - DRAW IT You are cloning an aardvark gene, using a...Ch. 20 - EVOLUTlON CONNECTION Ethical considerations aside,...Ch. 20 - Prob. 13TYUCh. 20 - Prob. 14TYUCh. 20 - The water in the Yellowstone National Park hot...
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