Laboratory Manual for Holes Human Anatomy & Physiology Fetal Pig Version
14th Edition
ISBN: 9781259295645
Author: Terry R. Martin
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 2, Problem F2.5A
FIGURE 2.5 Label the planes represented in this illustration.
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1.5
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5. (15 points) An individual comes into your clinic with a phenotype that
resembles Down's syndrome. You perform CGH by labeling the patient's
hobe DNA red and her mother's DNA green. Plot the expected results of the
Red:Green ratio if:
A. The cause of the syndrome was an inversion on one chromosome 21 in the child
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1.5
1.0
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0.5
21 p 12345678910 CEN q 123456789 10 11 12 13 14 15 16 17 18 19
B. The cause of the syndrome was a duplication of the material between 21q14 and
21q18 on one chromosome in the child
21 p 123456789 10 CEN q 12345678910 11 12 13 14 15 16 17 18 19
C. The mother carried a balanced translocation that segregated by adjacent
segregation in meiosis I and resulted in a duplication in the child of the material
distal to the translocation breakpoint at 21q14.
1.5
1.0
0.67
0.5
21 p 12345678910 CEN q 123456789 10 11 12 13 14 15 16 17 18 19
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4.
You find that all four flower color genes map to the second
chromosome, and perform complementation tests with deletions for each
gene. You obtain the following results:
(mutant a = blue, mutant b = white, mutant c = pink, mutant d = red)
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Results of Complementation tests
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Mutant a
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Del (2.2 -2.6)
blue
white
pink
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Del (2.3-2.8)
blue
white
pink
red
Del (2.1 -2.5)
blue
purple
pink
purple
Del (2.4-2.7)
purple
white
pink
red
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Indicate where each gene maps:
a
b
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1. Below is a pedigree of a rare trait that is associated with a variable number
repeat. PCR was performed on individuals using primers flanking the VNR,
and results are shown on the agarose gel below the pedigree.
I.1 1.2 II.1 II.2 II.3 II.4 II.5 II.6 11.7 III.1 III.2 III.3 III.4etum
A. (5 points) What is the mode of inheritance?
B. (10 points) Fill in the expected gel lanes for II.1, II.5, III.2, III.3 and III.4
C. (5 points) How might you explain the gel results for II.4?
Chapter 2 Solutions
Laboratory Manual for Holes Human Anatomy & Physiology Fetal Pig Version
Ch. 2 - Prob. F2.1ACh. 2 - FIGURE 2.2 Label the thoracic membranes and...Ch. 2 - FIGURE 2.5 Label the planes represented in this...Ch. 2 - Match the body cavities in column A with the...Ch. 2 - the organ systems in column A with the principal...Ch. 2 - Indicate whether each of the following sentences...Ch. 2 - Indicate whether each of the following sentences...Ch. 2 - Indicate whether each of the following sentences...Ch. 2 - Indicate whether each of the following sentences...Ch. 2 - Indicate whether each of the following sentences...
Ch. 2 - Indicate whether each of the following sentences...Ch. 2 - Indicate whether each of the following sentences...Ch. 2 - Indicate whether each of the following sentences...Ch. 2 - Indicate whether each of the following sentences...Ch. 2 - Prob. 3.10ACh. 2 - Indicate whether each of the following sentences...Ch. 2 - Indicate whether each of the following sentences...Ch. 2 - Prob. 4.1ACh. 2 - Prob. 5.1ACh. 2 - State the quadrant of the abdominopelvic cavity...Ch. 2 - Prob. 6.2CTCh. 2 - Prob. 6.3CTCh. 2 - Prob. 6.4CTCh. 2 - Prob. 6.5CTCh. 2 - Prob. 6.6CT
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