Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
Question
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Chapter 2, Problem 32CQ

(a)

Summary Introduction

To explain: Which proton is dissociated at a lower pH – the proton of the carboxylic acid group or the ammonium group of glycine hydrochloride (Cl-H3N+CH2COOH).

Concept introduction: As per chemistry, the substance which is capable of donating a proton (H+) is considered as an acid and is able to form a covalent bond with an electron. Also, the substance which accepts a proton is called a base. The pH of a solution is denoted as the negative logarithm of the hydrogen ion concentration of that solution. The pH in a solution decreases as H+ ion concentration increases in the solution.

(b)

Summary Introduction

To explain: The chemical formula to describe the dissociation of the first and second protons of glycine hydrochloride (Cl-H3N+CH2COOH)

Concept introduction: As per chemistry, the substance which is capable of donating a proton (H+) is considered as an acid and is able to form a covalent bond with an electron. Also, the substance which accepts a proton is called a base. The pH of a solution is denoted as the negative logarithm of the hydrogen ion concentration of that solution. The pH in a solution decreases as H+ ion concentration increases in the solution.

(c)

Summary Introduction

To calculate: The pK of the solution as per the given data.

Concept introduction: As per chemistry, the substance which is capable of donating a proton (H+) is considered as an acid and is able to form a covalent bond with an electron. Also, the substance which accepts a proton is called a base. The pH of a solution is denoted as the negative logarithm of the hydrogen ion concentration of that solution. The pH in a solution decreases as H+ ion concentration increases in the solution.

(d)

Summary Introduction

To sketch: The titration curve of glycine hydrochloride (Cl-H3N+CH2COOH) in an analogy with Fig. 2-18 in the textbook.

Concept introduction: As per chemistry, the substance which is capable of donating a proton (H+) is considered as an acid and is able to form a covalent bond with an electron. Also, the substance which accepts a proton is called a base. The pH of a solution is denoted as the negative logarithm of the hydrogen ion concentration of that solution. The pH in a solution decreases as H+ ion concentration increases in the solution.

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