The function of the translocon in co-translational transfer. Introduction: The process of co-translational protein transfer targets the protein into the secretory pathway. The co-translational pathway uses the signal recognition particle (SRP) for the delivery of secretory proteins to the endoplasmic reticulum (ER) membrane while they are still being synthesized by ribosomes. The translocon complex comprises multiple proteins and plays an important role in secretory transportation.

Question

Want to see the full answer?

Answer 1

Question

Chapter 19, Problem 20RQ

Summary Introduction

To review:

The function of the translocon in co-translational transfer.

Introduction:

The process of co-translational protein transfer targets the protein into the secretory pathway. The co-translational pathway uses the signal recognition particle (SRP) for the delivery of secretory proteins to the endoplasmic reticulum (ER) membrane while they are still being synthesized by ribosomes. The translocon complex comprises multiple proteins and plays an important role in secretory transportation.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Question 1. Enzymes, proteins and deoxyribonucleic acid (DNA) macromolecules. Enzymes are not only speed up the reaction, but also are necessary for DNA repreduction. are important biological a) Compare the process of protein synthesis between eukaryote mRNA and viral RNA b) With the aid of a diagram, draw an adapter molecule that recognizes the codons of mRNA and explain its functions in DNA translation.

Question 7: Peptide nucleic acids (PNAS) exhibit greater stability as heteroduplexes with DNA (ie PNA-DNA duplex) than does double-stranded DNA (i.e. DNA-DNA duplex). However, peptide nucleic acids lack charged groups, making them largely insoluble under near-physiological conditions in aqueous buffer. Provide (1) an explanation for the increased stability of PNA-DNA duplexes (hint: consider intermolecular forces). (2) Additionally, propose modification(s) of the PNA scaffold DNA that could increase solubility without drastically reducing duplex stability. PNA R1 HN но. Base Base o=P-O NH Base Base 8 o=P-O- NH 8. Base Base НО NH

QUESTION NO. 1 Patients with the rare genetic disease xeroderma pigmentosum (XP) are very sensitive to light and are highly susceptible to skin cancers. The study of such patients has enhanced our knowledge of DNA repair because XP is caused by defective DNA repair nucleotide excision repair. (A variant, XP-V, is deficient in postreplication repair.) In nucleotide excision repair A. removal of the damaged bases occurs on only one strand of the DNA. B. only thymine dimers generated by UV light can be removed . C. the excision nuclease is an exonuclease. D. a single multifunctional enzyme carries out the repair process. E. only the damaged nucleotides are removed. QUESTION NO.2 Homologous recombination: A. occurs only between two segments from the same DNA molecule. B. requires that a specific DNA sequence be present. C. requires one of the duplexes undergoing recombination be nicked in both strands. D. involves a…