Chapter 19, Problem 19.70QP

Interpretation Introduction

Interpretation:

The apparent contradiction in the two statements that say that the rate of a nonenzymatic reaction increases with temperature while the rate decreases for corresponding temperature increases in an enzymatic reaction has to be explained.

Concept Introduction:

All physiological reactions work most efficiently under optimum $\text{pH}$ and temperature. Variation in the optimum $\text{pH}$ or temperature impacts the environment of the substrate or the cytoplasmic region that can ultimately affect the activity of the enzyme, and thus the ability of the enzyme to form the enzyme-substrate complex is compromised.