Campbell Biology (11th Edition)
11th Edition
ISBN: 9780134093413
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Textbook Question
Chapter 18, Problem 7TYU
Absence of bicoid in mRNA from a Drosophila egg leads to the absence of anterior larval body parts and mirror-image duplication of posterior parts. This is evidence that the product of the bicoid gene
- (A) normally leads to formation of head structures.
- (B) normally leads to formation of taii structures.
- (C) is transcribed in the early embryo.
- (D) Is a protein present in all head structures.
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Which of the following statements is most consistent with the pattern of gene expression shown in the given graph?
(A) Repressors that bind to a regulatory sequence of Gene X are present in brain tissue but not in heart tissue. (B) Gene X is located within heterochromatin in brain tissue and within euchromatin in heart tissue.
(C) Small RNAs that help degrade Gene X mRNA are present in brain tissue but not in heart tissue
(D)Activators that bind to an enhancer of Gene X are present in brain tissue but not in heart tissue.
Homeotic genes(A) encode transcription factors that control the expression ofgenes responsible for specific anatomical structures.(B) are found only in Drosophila and other arthropods.(C) are the only genes that contain the homeobox domain.(D) encode proteins that form anatomical structures in the fly.
As we have learned in this chapter, the Nanos protein inhibits the translation of hunchback mRNA, lowering the concentration of Hunchback protein at the posterior end of a fruit-fly embryo and stimulating the differentiation of posterior characteristics. The results of experiments have demonstrated that the action of Nanos on hunchback mRNA depends on the presence of an 11-base sequence that is located in the 3′ untranslated region (3′ UTR) of hunchback mRNA. This sequence has been termed the Nanos response element (NRE). There are two copies of NRE in the 3′ UTR of hunchback mRNA. If a copy of NRE is added to the 3′ UTR of another mRNA produced by a different gene, that mRNA is repressed by Nanos. The repression is greater if several NREs are added. On the basis of these observations, propose a mechanism for how Nanos inhibits Hunchback translation.
Chapter 18 Solutions
Campbell Biology (11th Edition)
Ch. 18.1 - How does binding of the trp corepressor to the trp...Ch. 18.1 - Describe the binding of RNA Polymerase,...Ch. 18.1 - WHAT IF? A certain mutation in E. coli changes...Ch. 18.2 - In general, what are the effects of histone...Ch. 18.2 - MAKE CONNECTIONS Speculate about whether the same...Ch. 18.2 - Compare the roles of general and specific...Ch. 18.2 - Once mRNA encoding a particular protein reaches...Ch. 18.2 - WHAT IF? Suppose you compared the nucleotide...Ch. 18.3 - Compare miRNAs and siRNAs, including their...Ch. 18.3 - WH AT IF? Suppose the mRNA being degraded in...
Ch. 18.3 - MAKE CONNECTIONS Inactivation of one of the X...Ch. 18.4 - MAKE CONNECTIONS As you learned in Chapter 12,...Ch. 18.4 - MAKE CONNECTIONS Explain how the signaling...Ch. 18.4 - How do fruit fly maternal effect genes determine...Ch. 18.4 - Prob. 4CCCh. 18.5 - Prob. 1CCCh. 18.5 - Under what circumstances is cancer considered to...Ch. 18.5 - MAKE CONNECTIONS The p53 protein can activate...Ch. 18 - Compare and contrast the roles of a corepressor...Ch. 18 - Describe what must happen in a cell for a gene...Ch. 18 - Why are miRNAs called noncoding RNAs? Explsin how...Ch. 18 - Describe the two main processes that cause...Ch. 18 - Compare the usual functions of proteins encoded by...Ch. 18 - If a particular operon encodes enzymes for making...Ch. 18 - Muscle cells differ from nerve cells mainly...Ch. 18 - The functioning of enhancers is an example of (A)...Ch. 18 - Cell differentiation always involves (A)...Ch. 18 - Which of the following is an example of...Ch. 18 - What would occur if the repressor of an inducible...Ch. 18 - Absence of bicoid in mRNA from a Drosophila egg...Ch. 18 - Which of the following statements about the DNA in...Ch. 18 - Within a cell, the amount of protein made using a...Ch. 18 - Prob. 10TYUCh. 18 - draw it The diagram below shows five genes,...Ch. 18 - Prob. 12TYUCh. 18 - Prob. 13TYUCh. 18 - SCIENCE. TECHNOLOGY, AND SOCIETY Trace amounts of...Ch. 18 - WRITE ABOUT A THEME: INTERACTIONS In a Short essay...Ch. 18 - SYNTHESIZE YOUR KNOWLEDGE The flashlight fish has...
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- Which of the following is an example of post-transcriptionalcontrol of gene expression?(A) the addition of methyl groups to cytosine bases of DNA(B) the binding of transcription factors to a promoter(C) the removal of introns and alternative splicing of exons(D) gene amplification contributing to cancerarrow_forwardSuppose expression of gene A is limited to the middle part of the early mouse embryo. Expression of gene B is located on the posterior and anterior ends of the early mouse embryo, but not in the middle. When gene B is mutated, expression of gene A is distributed over the whole embryo. What is a likely explanation for this data? a) Gene A acts as an activator of gene B. Ob) Gene A acts as a repressor of gene B. O c) Gene B acts as an activator of gene A. () d) Gene B acts as a repressor of gene A.arrow_forwardWe know that eukaryote gene regulation can occur at any point in the process of gene expression. (a) What is the final step where gene expression control may occur in the process of protein expression ? (b) Is this a cellular energy efficient or inefficient mechanism of gene regulation? Explain.arrow_forward
- Another way to study the role of proteins (e.g., transcription factors) that function in development is to microinject the mRNA that encodes a protein, or the purified protein itself, into an oocyte or embryo, and then determine how this affects the subsequent development of the embryo, larva, and adult. For example, if Bicoid protein is injected into the posterior region of an oocyte, the resulting embryo will develop into a larva that has anterior structures at both ends. Based on your understanding of the function of each developmental gene, what would be the predicted phenotype if the following proteins or mRNAs were injected into normal oocytes? A. Nanos mRNA injected into the anterior end of an oocyte B. Antp protein injected into the posterior end of an embryo C. Toll mRNA injected into the dorsal side of an early embryoarrow_forwardMaternal and zygotic mRNAs regulate embryonic development by determining major body axes. Two of the these mRNAs code for the proteins ____ (of maternal origin) and (of zygotic origin), which are morphogens that accumulate at the end of the egg that will become the anterior end of the embryo, whereas two other mRNAs code for the morphogens ____ (maternal origin) and ____ (zygotic origin), which accumulate at the opposite end of the egg and determine the posterior end of the embryo. The dorso-ventral axis of the embryo is established by two morphogens coded for by maternal mRNAs: (1) ____, which is transcribed in the egg nucleus and accumulates in a crescent on the side of the egg that will become the dorsal surface; and (2) ____, which is transported after fertilization into blastodermal cells that will become the ventral surface, and in these cells activates the zygotic gene ____, which produces a protein that diffuses to the blatodermal cells at the opposite side of the egg and…arrow_forwardWhat would be the most likely effect of inhibiting the translation of hunchback mRNA throughout a Drosophila embryo?arrow_forward
- (a) Describe how dna binding proteins contact the dna (b)How does the acetylation of lysines on the N-terminal tails of histones influences gene expression?arrow_forwardAn embryologist measures the concentrations of three morphogens (A, B, C) in a row of cells across an embryo, from anterior to posterior. The morphogens cause the expression of various colored pigments as indicated in the graphs. Anterior Posterior Expression of Blue protein only [A] Expression of Red protein only Expression of Green protein only Anterior Posterior [B] Repression of Purple protein Activation of Red protein Anterior Posterior [C] Activation of Yellow protein Which shows the correct expression of pigments expressed in response to Morphogen A? Anterior Posterior Anterior Posterior Anterior Posterior Anterior Posteriorarrow_forwardBased on the photographs shown, in which segments is the Antp gene normally expressed?arrow_forward
- A mutation occurs in a gene, resulting in it being expressed at the wrong time during development. Where is the mutation most likely to be found? a) In the transcription start site (TSS) b) In a TF binding site in the cis-regulatory region c) In the coding sequence d) In the 5' UTRarrow_forwardWhich of the following are possible reasons that a cell would regulate its expression of a gene? (Select all that apply.) (a) an increased need for a particular enzyme (b) a decreased need for a particular enzyme (c) increasing temperature in the external environment (d) changing needs as an organism ages (e) deatharrow_forwardEarly development depends on the temporal and spatial interplay between maternally supplied material and mRNA and the onset of zygotic gene expression. Maternally encoded mRNAs must be produced, positioned, and degraded [Surdej and Jacobs-Lorena (1998). Mol. Cell Biol. 18:2892–2900]. For example, transcription of the bicoid gene that determines anterior– posterior polarity in Drosophila is maternal. The mRNA is synthesized in the ovary by nurse cells and then transported to the oocyte, where it localizes to the anterior ends of oocytes. After egg deposition, bicoid mRNA is translated and unstable bicoid protein forms a decreasing concentration gradient from the anterior end of the embryo. At the start of gastrulation, bicoid mRNA has been degraded. Consider two models to explain the degradation of bicoid mRNA: (1) degradation may result from signals within the mRNA (intrinsic model), or (2) degradation may result from the mRNA’s position within the egg (extrinsic model).…arrow_forward
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