Anatomy and Physiology
9th Edition
ISBN: 9781260256000
Author: SALADIN
Publisher: MCG
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 18, Problem 5TYC
Summary Introduction
Summary:
Although fibrinogen and prothrombin are equally necessary for blood clotting, fibrinogen is about 4% of the plasma, whereas prothrombin is present only in small traces.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Human serum albumin is another protein that has an extremely long half life in the body. Due to this, the low probability event, glycation does take place. Write a rate law for this reaction:
Rate = k[glucose]
Rate = k[hemoglobin]
Rate = k [glucose hemoglobin albumin]
The inner leaflet (monolayer) of the human erythrocyte membrane consists predominantly of phosphatidylethanolamine and phosphatidylserine. The outer leaflet consists predominantly of phosphatidylcholine and sphingomyelin. Although the phospholipid components of the membrane can diffuse in the fluid bilayer, this sidedness is preserved at all times. How?
Cows that graze on spoiled sweet clover, which contains dicoumarol, die from hemorrhagic disease. The cause of death is defective prothrombin. However, the amino acid composition of the defective prothrombin is identical to that of normal prothrombin. What is the mechanism of action of dicoumarol? Why are the amino acid compositions of the defective and normal prothrombin the same?
Chapter 18 Solutions
Anatomy and Physiology
Ch. 18.1 - Identify at least two each of the transport,...Ch. 18.1 - Prob. 2BYGOCh. 18.1 - List the three major classes of plasma proteins....Ch. 18.1 - Prob. 4BYGOCh. 18.1 - Prob. 5BYGOCh. 18.1 - Prob. 1AYLOCh. 18.1 - Prob. 2AYLOCh. 18.1 - Prob. 3AYLOCh. 18.1 - Prob. 4AYLOCh. 18.1 - Prob. 5AYLO
Ch. 18.1 - Prob. 6AYLOCh. 18.1 - Prob. 7AYLOCh. 18.2 - Describe the size, shapte, and contents of an...Ch. 18.2 - Prob. 7BYGOCh. 18.2 - Prob. 8BYGOCh. 18.2 - Prob. 9BYGOCh. 18.2 - Prob. 10BYGOCh. 18.2 - Prob. 11BYGOCh. 18.2 - Prob. 12BYGOCh. 18.2 - Prob. 1AYLOCh. 18.2 - Prob. 2AYLOCh. 18.2 - Prob. 3AYLOCh. 18.2 - Three ways of quantifying the RBCs and hemoglobin...Ch. 18.2 - Prob. 5AYLOCh. 18.2 - Prob. 6AYLOCh. 18.2 - Prob. 7AYLOCh. 18.2 - Prob. 8AYLOCh. 18.2 - Prob. 9AYLOCh. 18.2 - Prob. 10AYLOCh. 18.2 - Causes and effects of hemoglobin deficiencies and...Ch. 18.3 - Prob. 13BYGOCh. 18.3 - Prob. 14BYGOCh. 18.3 - Prob. 15BYGOCh. 18.3 - Prob. 16BYGOCh. 18.3 - Prob. 1AYLOCh. 18.3 - Prob. 2AYLOCh. 18.3 - Prob. 3AYLOCh. 18.3 - Prob. 4AYLOCh. 18.3 - Prob. 5AYLOCh. 18.3 - Prob. 6AYLOCh. 18.3 - Hemolytic disease of the newborn; why it seldom...Ch. 18.4 - Prob. 17BYGOCh. 18.4 - Prob. 18BYGOCh. 18.4 - Prob. 19BYGOCh. 18.4 - Prob. 20BYGOCh. 18.4 - Prob. 21BYGOCh. 18.4 - Prob. 1AYLOCh. 18.4 - Prob. 2AYLOCh. 18.4 - Prob. 3AYLOCh. 18.4 - Prob. 4AYLOCh. 18.4 - Prob. 5AYLOCh. 18.4 - Prob. 6AYLOCh. 18.4 - Prob. 7AYLOCh. 18.5 - Prob. 22BYGOCh. 18.5 - Prob. 23BYGOCh. 18.5 - Prob. 24BYGOCh. 18.5 - Prob. 25BYGOCh. 18.5 - Prob. 26BYGOCh. 18.5 - Prob. 1AYLOCh. 18.5 - Prob. 2AYLOCh. 18.5 - Prob. 3AYLOCh. 18.5 - Prob. 4AYLOCh. 18.5 - Prob. 5AYLOCh. 18.5 - Prob. 6AYLOCh. 18.5 - Prob. 7AYLOCh. 18.5 - Prob. 8AYLOCh. 18.5 - Prob. 9AYLOCh. 18.5 - Prob. 10AYLOCh. 18.5 - Prob. 11AYLOCh. 18.5 - Terms for unwanted or inappropriate clotting in a...Ch. 18.5 - Prob. 13AYLOCh. 18 - Antibodies belong to a class of plasma proteins...Ch. 18 - Prob. 2TYRCh. 18 - Prob. 3TYRCh. 18 - Prob. 4TYRCh. 18 - Prob. 5TYRCh. 18 - Prob. 6TYRCh. 18 - Prob. 7TYRCh. 18 - Prob. 8TYRCh. 18 - Prob. 9TYRCh. 18 - Prob. 10TYRCh. 18 - Prob. 11TYRCh. 18 - Prob. 12TYRCh. 18 - Prob. 13TYRCh. 18 - Prob. 14TYRCh. 18 - Prob. 15TYRCh. 18 - Prob. 16TYRCh. 18 - Prob. 17TYRCh. 18 - Prob. 18TYRCh. 18 - Prob. 19TYRCh. 18 - Prob. 20TYRCh. 18 - Prob. 1BYMVCh. 18 - Prob. 2BYMVCh. 18 - Prob. 3BYMVCh. 18 - Prob. 4BYMVCh. 18 - Prob. 5BYMVCh. 18 - Prob. 6BYMVCh. 18 - Prob. 7BYMVCh. 18 - Prob. 8BYMVCh. 18 - Prob. 9BYMVCh. 18 - Prob. 10BYMVCh. 18 - Prob. 1WWTSCh. 18 - Prob. 2WWTSCh. 18 - Prob. 3WWTSCh. 18 - Prob. 4WWTSCh. 18 - Prob. 5WWTSCh. 18 - Prob. 6WWTSCh. 18 - Prob. 7WWTSCh. 18 - All formed elements of the blood except platelets...Ch. 18 - When RBCs die and break down, the globin moiety of...Ch. 18 - Prob. 10WWTSCh. 18 - Prob. 1TYCCh. 18 - Prob. 2TYCCh. 18 - Prob. 3TYCCh. 18 - Prob. 4TYCCh. 18 - Prob. 5TYC
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Hemoglobin glycation (so named to distinguish it from glycosylation, which is the enzymatic transfer of glucose to a protein) is a non-enzymatic process that involves reaction of the N-terminal amino group of hemoglobin and glucose. The amount of glycated hemoglobin (GHB) is usually about 5% of total hemoglobin (and corresponds to a blood glucose concentration of 120 mg/100 mL). However, in people with untreated diabetes this value may be as high as 13%, which indicates an average blood level of about 300 mg/100 mL -dangerously high. One of the aims of insulin therapy is to maintain GHB values of about 7%. Draw a possible chemical scheme for the glycation of hemoglobin.arrow_forwardAcid phosphatases are an important group of enzymes that can be detected in human blood serum. Under slightly acidic conditions (pH 5.0), this group of enzymes can hydrolyze biological phosphate esters as follows in the picture Acid phosphatases are produced and can be detected in erythrocytes, kidney, spleen, the liver, and prostate gland. The enzyme from the prostate gland is clinically important because an increased activity in the blood is frequently an indication of cancer of the prostate gland.Tartrate ion can strongly inhibit the phosphatase from the prostate gland, but not acid phosphatases from other tissues. How can you use the information above to develop a specific procedure for measuring the activity of the acid phosphatase of the prostate gland in human blood serum?arrow_forwardHbA1c is a glycated hemoglobin in which a glucose molecule is covalently bound to the N-terminal valine of a hemoglobin subunit. True Falsearrow_forward
- Acid phosphatases are an important group of enzymes that can be detected in human blood serum. Under slightly acidic conditions (pH 5.0), this group of enzymes can hydrolyze biological phosphate esters.Acid phosphatases are produced and can be detected in erythrocytes, kidney, spleen, the liver, and prostrate gland. The enzyme from the prostrate gland is clinically important because an increased activity in the blood is frequently an indication of cancer of the prostrate gland. Tartrate ion can strongly inhibit the phosphatase from the prostrate gland, but not acid phosphatases from other tissues. How can you use the information above to develop a specific procedure for measuring the activity of the acid phosphatase of the prostrate gland in human blood serum?arrow_forwardCarbonic anhydrase of erythrocytes (Mr 30,000) has one of the highest turnover numbers known. It catalyzes the reversible hydration of CO₂. H₂O + CO₂ 2 H₂CO3 This is an important process in the transport of CO₂ from the tissues to the lungs. If 5 µg of pure carbonic anhydrase catalyzes the hydration of 0.35 g of CO₂ in 1 min at 37 °C at Vmax, what is the turnover number (kcat) of carbonic anhydrase? Kcat 2.0466 ×107 Incorrect min-1arrow_forwardThe action of this enzyme found in Beano alpha-galactosidase can also according to many sources be used to remove ____________ from the red blood cells of the B blood group and convert them to the O blood group. Since the _________ molecules (composed of many monomers) are connnected to protein on the membrane and also the cell membrane of the red blood cell itself; therefore these molecules help create cell identity and recognition, and when the are connected to proteins they are known as _________ , but if they are connected to the cell membrane itself they are known as ____________. This is a good question for reviewing the structures on the cell membrane as well. The only difference between the B-blood type and the O-blood type is ________. The following is a diagram of the differences of these molecules that determine blood type. List of answers: disaccharid, proteins ,dehydration synthesis ,nucleotide ,amino acids ,nucleic acids ,lactose ,fructose ,sucrose ,hydrolysis…arrow_forward
- Explain why the proteins involved in blood clotting, fi brin and thrombin, are fi rst synthesized as the zymogens fi brinogen and prothrombin, respectively.arrow_forwardAcid phosphatases are an important group of enzymes that can be detected in human bloodserum. Under slightly acidic conditions (pH 5.0), this group of enzymes can hydrolyzebiological phosphate esters as follows:R-O-P-O3-2 + H2O -----> R-OH + HO-P-O3-2Acid phosphatases are produced and can be detected in erythrocytes, kidney, spleen, the liver,and prostrate gland. The enzyme from the prostrate gland is clinically important because anincreased activity in the blood is frequently an indication of cancer of the prostrate gland.Tartrate ion can strongly inhibit the phosphatase from the prostrate gland, but not acidphosphatases from other tissues. How can you use the information above to develop a specific procedure for measuring the activity of the acid phosphatase of the prostrate gland in humanblood serum?arrow_forward"Hemoglobin can be in either an oxy- or deoxy- state at a given pH. Given the appropriate pKa values, calculate fraction protonated at a given pH" How would I do this?arrow_forward
- Think about our previous lecture, we discussed red blood cell’s (RBC) shunt that takes place during glycolysis. You know that the main function of RBCs is to carry O2 from lungs to tissues. Please kindly discuss this function at the molecular level (at the level of hemoglobin structure α & β chains) taking in consideration 2, 3-BPG.arrow_forwardThe venom of the Eastern diamondback rattler and the Indian cobra contains phospholipase A2, which catalyzes the hydrolysis of fatty acids at the C-2 position of glycerophospholipids. The phospholipid products of this reaction, in high enough concentrations, can act as detergents, dissolving the membranes of erythrocytes and lysing the cells. The pain and inflammation caused by a snake bite can be treated with certain steroids. What is the basis of this treatment?arrow_forwardOxygen is transported from your lungs to tissues throughout your body by red blood cells. Approximately 2.4 million new red blood cells are produced per second in human adults. The functional lifetime of a red blood cell is about 100-120 days, during which time the red blood cells are continually moved by the blood flow. Which of the following enzyme deficiencies could possibly cause hemolytic anemia due to breakdown and loss of red blood cells? Isocitrate dehydrogenase, a Krebs cycle enzyme Pyruvate kinase, a glycolysis enzyme Succinyl-CoA synthetase, a Krebs cycle enzyme Ubiquinone oxidoreductase, complex I of the electron transport chainarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Anaerobic Respiration; Author: Bozeman Science;https://www.youtube.com/watch?v=cDC29iBxb3w;License: Standard YouTube License, CC-BY