Microbiology: An Introduction (13th Edition)
13th Edition
ISBN: 9780134605180
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case, Derek Weber, Warner Bair
Publisher: PEARSON
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Chapter 18, Problem 2A
Summary Introduction
To write:
Many serological tests use the antibodies against the particular pathogen but the Salmonella typhi has three antigens, such as the IgM antibodies production is deficient in nature, and production is made by hybridoma technology.
Given:
Production of antibodies by the Salmonella typhi for the serological test to confirm the presence of antigen in humans.
Introduction:
Salmonella typhi is a gram negative bacteria which is the causative agent for typhoid fever. When it is infected to a person, his immune system produces IgG, IgM and IgA antibodies, since it has three antigens but there is a high specificity in IgM antibody compared to IgG antibody. Widal test often gives false-positive results with other gram negative bacteria.
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Students have asked these similar questions
To diagnosis, we used a procedure known as a "sandwich ELISA" (Enzyme-Linked Immunosorbent Assay).
1.In the "ELISA sandwich," what is the "meat"?
2.Both patients A and B had positive results. Why are these two patients' outcomes so different?
3.What is one potential cause of an ELISA false negative result? What is one potential cause of an ELISA false positive result? What is another example of how an ELISA assay should be used?
In (b), why would it be more efficient to use labeled anti-human IgG rather than label the patient’s antibodies?
What are the differences between “O” and “H” antigen?
Differentiate Widal from Weil-Felix test.
The strains of Proteus vulgaris are used in Weil-felix reaction. Explain why.
Chapter 18 Solutions
Microbiology: An Introduction (13th Edition)
Ch. 18 - Which could cause the disease it is supposed to...Ch. 18 - Define the following terms, and give an example of...Ch. 18 - DRAW IT Label the components of the direct and...Ch. 18 - How are monoclonal antibodies produced? What is...Ch. 18 - Explain the effects of excess antigen and antibody...Ch. 18 - Prob. 6RCh. 18 - How does the antigen in an agglutination reaction...Ch. 18 - Match the following serological tests in column A...Ch. 18 - Prob. 9RCh. 18 - Prob. 10R
Ch. 18 - Prob. 1MCQCh. 18 - Prob. 2MCQCh. 18 - Prob. 3MCQCh. 18 - Prob. 4MCQCh. 18 - Prob. 5MCQCh. 18 - Prob. 6MCQCh. 18 - Prob. 7MCQCh. 18 - Test used to identify rabies virus in the brain of...Ch. 18 - Prob. 9MCQCh. 18 - Prob. 10MCQCh. 18 - What problems are associated with the use of live...Ch. 18 - Prob. 2ACh. 18 - Prob. 3ACh. 18 - Which of the following is proof of a disease...Ch. 18 - Prob. 2CAECh. 18 - Prob. 3CAE
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