How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication . Introduction: To convert genotype to phenotype , the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

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Answer 1

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Chapter 15, Problem 1IQ

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To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

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Which of the following features is common to both DNA replication and RNA transcription? Both RNA and DNA polymerase form a sugar-phosphate bond between the 3' hydroxyl and the 5' phosphate. Both RNA and DNA polymerase require oligonucleotide priming. Both RNA and DNA polymerase incorporate deoxyribonucleotides into the growing sequence. Both RNA and DNA polymerase initiate at promoter sequences. Both RNA and DNA polymerase have extensive proofreading editing.

Which of the following processes of genetic information flow can occur under lab conditions, but has never been observed to occur under natural conditions (either in living cells or in viruses)? transcription of RNA from a DNA template (using DNA-dependent-RNA-polymerase) self-replication of RNA from an RNA template (using RNA-dependent-RNA-polymerase) direct-translation of protein from a DNA template (using special ribosomes) self-replication of DNA from a DNA template (using DNA-dependent-DNA-polymerase) translation of protein from an RNA template (using ordinary ribosomes)

Why does DNA replication need to be error-free? Why does the DNA need to be a “careful reader?”

Answer 2

Question

Chapter 15, Problem 1IQ

Summary Introduction

To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

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Answer 3

Question

Chapter 15, Problem 1IQ

Summary Introduction

To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

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Answer 4

Question

Chapter 15, Problem 1IQ

Summary Introduction

To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

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Answer 5

Chapter 15, Problem 1IQ

Summary Introduction

To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

Answer 6

Chapter 15, Problem 1IQ

Summary Introduction

To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Answer 7

Chapter 15, Problem 1IQ

Summary Introduction

To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Answer 8

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

Answer 9

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

Answer 10

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Answer 13

Ch. 15.1 - Prob. 1LO Ch. 15.1 - Prob. 2LO Ch. 15.1 - List the roles played by RNA in gene expression.Ch. 15.2 - Prob. 1LO Ch. 15.2 - Describe the characteristics of the genetic code.Ch. 15.2 - Prob. 3LO Ch. 15.3 - Prob. 1LO Ch. 15.3 - Differentiate among initiation, elongation, and...Ch. 15.3 - Prob. 3LO Ch. 15.4 - Prob. 1LO

Solution Summary: The author explains how the absence of proofreading capacity for RNA polymerase affects the rate of error in the transcription process.

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