The method of synthesis of hept-5-yn-1-ol from 4-bromobutan-1-ol with the help of a protecting group is to be stated. Concept introduction: Silyl ethers are used as alcohol-protecting groups. A good protecting group should be easy to add and remove. An ether protecting group is difficult to deprotect. Strong acids are required to deprotect it. However, silyl ethers are easily removed as compared to carbon-based ethers. The silyl ether is stablised by three bulky isopropyl groups.

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Answer 1

Question

Chapter 14.10B, Problem 14.19P

Interpretation Introduction

Interpretation:

The method of synthesis of hept-5-yn-1-ol from 4-bromobutan-1-ol with the help of a protecting group is to be stated.

Concept introduction:

Silyl ethers are used as alcohol-protecting groups. A good protecting group should be easy to add and remove. An ether protecting group is difficult to deprotect. Strong acids are required to deprotect it. However, silyl ethers are easily removed as compared to carbon-based ethers. The silyl ether is stablised by three bulky isopropyl groups.

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Answer 2

Question

Chapter 14.10B, Problem 14.19P

Interpretation Introduction

Interpretation:

The method of synthesis of hept-5-yn-1-ol from 4-bromobutan-1-ol with the help of a protecting group is to be stated.

Concept introduction:

Silyl ethers are used as alcohol-protecting groups. A good protecting group should be easy to add and remove. An ether protecting group is difficult to deprotect. Strong acids are required to deprotect it. However, silyl ethers are easily removed as compared to carbon-based ethers. The silyl ether is stablised by three bulky isopropyl groups.

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Answer 3

Question

Chapter 14.10B, Problem 14.19P

Interpretation Introduction

Interpretation:

The method of synthesis of hept-5-yn-1-ol from 4-bromobutan-1-ol with the help of a protecting group is to be stated.

Concept introduction:

Silyl ethers are used as alcohol-protecting groups. A good protecting group should be easy to add and remove. An ether protecting group is difficult to deprotect. Strong acids are required to deprotect it. However, silyl ethers are easily removed as compared to carbon-based ethers. The silyl ether is stablised by three bulky isopropyl groups.

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Answer 4

Question

Chapter 14.10B, Problem 14.19P

Interpretation Introduction

Interpretation:

The method of synthesis of hept-5-yn-1-ol from 4-bromobutan-1-ol with the help of a protecting group is to be stated.

Concept introduction:

Silyl ethers are used as alcohol-protecting groups. A good protecting group should be easy to add and remove. An ether protecting group is difficult to deprotect. Strong acids are required to deprotect it. However, silyl ethers are easily removed as compared to carbon-based ethers. The silyl ether is stablised by three bulky isopropyl groups.

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Answer 5

Chapter 14.10B, Problem 14.19P

Interpretation Introduction

Interpretation:

The method of synthesis of hept-5-yn-1-ol from 4-bromobutan-1-ol with the help of a protecting group is to be stated.

Concept introduction:

Silyl ethers are used as alcohol-protecting groups. A good protecting group should be easy to add and remove. An ether protecting group is difficult to deprotect. Strong acids are required to deprotect it. However, silyl ethers are easily removed as compared to carbon-based ethers. The silyl ether is stablised by three bulky isopropyl groups.

Answer 6

Chapter 14.10B, Problem 14.19P

Interpretation Introduction

Interpretation:

The method of synthesis of hept-5-yn-1-ol from 4-bromobutan-1-ol with the help of a protecting group is to be stated.

Concept introduction:

Silyl ethers are used as alcohol-protecting groups. A good protecting group should be easy to add and remove. An ether protecting group is difficult to deprotect. Strong acids are required to deprotect it. However, silyl ethers are easily removed as compared to carbon-based ethers. The silyl ether is stablised by three bulky isopropyl groups.

Answer 7

Chapter 14.10B, Problem 14.19P

Interpretation Introduction

Interpretation:

The method of synthesis of hept-5-yn-1-ol from 4-bromobutan-1-ol with the help of a protecting group is to be stated.

Concept introduction:

Silyl ethers are used as alcohol-protecting groups. A good protecting group should be easy to add and remove. An ether protecting group is difficult to deprotect. Strong acids are required to deprotect it. However, silyl ethers are easily removed as compared to carbon-based ethers. The silyl ether is stablised by three bulky isopropyl groups.

Answer 8

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Answer 9

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Answer 10

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Answer 11

Ch. 14.2C - Rank the given solvents in decreasing order of...Ch. 14.2D - Prob. 14.2P Ch. 14.2D - In the presence of 18-crown-6, potassium...Ch. 14.3B - Give a common name (when possible) and a...Ch. 14.3C - Prob. 14.5P Ch. 14.3C - Name the following heterocyclic ethers.Ch. 14.4 - Propose a fragmentation to account for each...Ch. 14.5 - Prob. 14.8P Ch. 14.5 - Prob. 14.9P Ch. 14.6 - Prob. 14.10P

Solution Summary: The author explains the method of synthesis of hept-5-yn-1-ol and the protection group triisopropylsilyl.

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