Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
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Chapter 14, Problem 11TYPSS
SOCIETY As a genetic counselor, you advise couples about the possibility of genetic disease in their offspring. This morning you met with an engaged couple, both of whom are
• How would you advise this couple?
• The sister of this man is planning to marry his fiancée'sbrother. How would you advise this second couple?
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YOUR SISTER DIED FROM TAY-SACHS DISEASE, INHERITED AS A RECESSIVE ALLELE (t). you're married and planning to start your family. you're worried about the disease and decide to have genetic testing to see if you or your spouse is a carrier of the tay-sachs allele. the test results show that you're a carrier of the allele, but your spouse isn't. what is the probability that you and your spouse will have a child with tay-sachs disease? show your work.
X‑linked, recessive diseases, such as hemophilia, are extremely rare in the population. However, many women are carriers and show no sign of the disease. The pedigree illustrates the inheritance of an X‑linked, recessive disease.
Determine whether the unknown individuals are affected by the disease, unaffected by the disease, or carriers of the X‑linked recessive allele. Unaffected individuals are not carriers of the X‑linked recessive allele.
A woman knows that her mother is a carrier of Kartagener’s syndrome (an autosomal recessive disorder). The woman does not know if either she or her husband are carriers. The couple wants to have a child, but is worried about whether or not they could have a child with Kartagener’s syndrome. Should the couple seek the advice of a genetic counselor? In other words, is there a chance they could have an affected child? If there is a chance, please make sure your answer includes the specific parental genotypes necessary to make this possible.
Chapter 14 Solutions
Biological Science (7th Edition)
Ch. 14 - 1. The genes for the trails that Mendel worked...Ch. 14 - Example Problem Two black female mice are crossed...Ch. 14 - Prob. 5TYKCh. 14 - Prob. 6TYPSSCh. 14 - Prob. 7TYPSSCh. 14 - 11. In garden peas, yellow seeds (Y) are dominant...Ch. 14 - Prob. 9TYPSSCh. 14 - The smooth feathers on the back of the neck in...Ch. 14 - SOCIETY As a genetic counselor, you advise couples...Ch. 14 - 15. Suppose you are heterozygous for two genes...
Ch. 14 - Suppose a woman with blood type O married a man...Ch. 14 - Prob. 14TYPSSCh. 14 - Society Two mothers give birth to sons at the same...Ch. 14 - Prob. 16TYPSSCh. 14 - QUANTITATIVE Recall that hemophilia is an X-linked...Ch. 14 - Prob. 18PIATCh. 14 - Given the pedigree, what is the most likely mode...Ch. 14 - Prob. 20PIATCh. 14 - QUANTITATIVE If the son with ALD in the third...Ch. 14 - Prob. 22PIATCh. 14 - Prob. 23PIAT
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- A 20-year-old woman comes to your genetic counselling center because she knows that Huntington disease occurs in members of her family. Huntington is an autosomal dominant disease that often becomes apparent around 35–40 years of age. Her paternal grandfather was afflicted, but so far her 41 year old father shows no symptoms. Her two great-great grandmothers on her father's side were healthy well into their 90s, and one of her great-great grandfathers died of unknown causes at 45. Testing for Huntington disease is extremely expensive, but she is concerned that she may fall victim to this disease and wants to plan her life accordingly. After examining her pedigree you advise her to: not get tested because her father is only a carrier and it is very unlikely her mother is a carrier. not get tested because there is no possibility that she is homozygous. get tested because her father could be a carrier. not get tested because only males in her family get the disease. not get tested…arrow_forwardIn man, muscular dystrophy is a condition in which the muscles waste away during early life and may result in a shorter life expectancy. It is due to a sex-linked, recessive gene. A certain couple has five children – three boys (ages 1yr, 3yrs, and 10yrs old) and two girls (ages 5yrs and 7yrs old). The oldest boy shows the symptoms of this disease. You are their family physician and they come to you for advice. What would you tell them about the chances of their other children developing the disease?arrow_forwardYou are a genetic counselor. How would you advise a couple who wants to know their chances of having a baby with Duchenne-muscular dystrophy. Hannah is not a carrier, but her husband Barry has a brother, James, who died from the disease. Duchenne-muscular dystrophy is an x-linked condition, the allele responsible is recessive and people who have the disease die in childhood. a)What are Hannah’s and Barry’s chances of having a baby with Duchenne-muscular dystrophy? b)What are the chances of Barry’s sister having a baby with the disease?arrow_forward
- Geneticists are concerned about three different genetic conditions present within their family. Achondroplasia is an autosomal dominant genetic disorder that results in short-limbed dwarfism. (A = achondroplasia allele; a = average height allele). Red-Green Color blindness is an X-linked recessive genetic disorder (Xc = color blindness allele; XC = normal color vision allele). The 7-year-old son has an autosomal recessive form of deafness. (h = deafness allele; H = normal hearing allele.) All three family members were karyotyped, and additional genetic testing was performed to determine the chromosomal location of the genes being studied. The figures below show the karyotypes of the mother and father with respect to the chromosomes containing the three genes mentioned above. Question: The couple’s 7-year-old son has all three of these genetic conditions (achondroplasia, color blindness and deafness). Taking into consideration the genotypes of his parents, what is the complete…arrow_forwardTwo mothers give birth to sons at the same time at a busy urban hospital. The son of mother 1 is afflicted with hemophilia, a disease caused by an X-linked recessive allele. Neither parent has the disease. Mother 2 has a normal son, despite the fact that the father has hemophilia. Several years later, couple 1 sues the hospital, claiming that these two newborns were swapped in the nursery following their birth. As a genetic counselor, you are called to testify. What information can you provide the jury concerning the allegation?arrow_forwardA couple enters your genetic counseling clinic for some family planning advice. The woman’s father was color blind, but her own vision is normal. The man has no family history of color blindness. Neither the man nor woman have any known history of hemophilia, but their first child (a boy) has hemophilia. They ask you to calculate the chance that their nextchild will be affected by one or both conditions. You remember from your genetics training that these are both X-linked recessive conditions and that they are closely linked: in fact, their genetic loci are separated by only 10cM! During the interview with this couple, you draw the following pedigree to represent their information. Given what you know, determine for this couple what chance they have of each of the following (in the table).arrow_forward
- Huntington's disease is an inherited autosomal dominant disorder that can affect both men and women. Imagine a couple has had seven children, and later in life, the husband develops Huntington's disease. He is tested and it is discovered he is heterozygous for the disease allele, Hh. The wife is also genetically tested for the Huntington's disease allele, and her test results show she is unaffected, hh. What is the percent probability that the first child of this couple will have Huntington's disease? probability: % What is the percent probability that two of the seven children will have Huntington's disease? probability: %arrow_forwardA couple comes to you, a genetics counselor, asking for you to explain to them their risk of having a child with cystic fibrosis. Cystic fibrosis is a recessive condition that impacts the lungs and the digestive system. The man, Julian, has a brother with the condition. He was tested for the gene, and he found out that he is a carrier (Ff), and his significant other, Gabby, is also a carrier (Ff). Use this information to answer the quesitons below. Identify the genotype of Julian. Homozygous recessive Homozygous dominat Heterozygousarrow_forwardAmanda Sefton (Daytripper) has normal fingers and toes and normal color vision. Her mother is normal in all respects, but her father is color blind (X- linked recessive) and syndactylous (autosomal dominant). Kurt Wagner (Nightcrawler) is color blind and syndactylous. His mother has normal color vision and normal fingers and toes, but he didn't know his father. As their genetic counselor, answer the following questions based on Kurt and Amanda marrying and starting a family. What is the probability of having a syndactylous boy that is color blind? (Enter your answer as a decimal; Example = 0.8782)arrow_forward
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