Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 11, Problem 2P
Interpretation Introduction

(a) Interpretation:

Determination of whether the following intracellular concetration ratio will be 1, >1, or <1: a. [NAD+]/ [NADH].

Concept introduction:

The major electron donors required for reductive biosynthesis is nicotinamide adenine dinucleotide phosphate (NADPH). NADPH and NADP+ are similar to NADH and NAD+ respectively. The nicotinamide nucleotide-linked enzymes which act in catabolic direction use NAD+/ NADH, whereas those which act in anabolic reactions uses NADP+/NADPH.

Interpretation Introduction

(b) Interpretation:

Determination of whether the following intracellular concetration ratio will be 1, >1, or <1: b. [NADP+/[NADPH].

Concept introduction:

The major electron donors required for reductive biosynthesis is nicotinamide adenine dinucleotide phosphate (NADPH). NADPH and NADP+ are similar to NADH and NAD+ respectively. The nicotinamide nucleotide-linked enzymes which act in catabolic direction use NAD+/ NADH, whereas those which act in anabolic reactions uses NADP+/NADPH.

Interpretation Introduction

(c) Interpretation:

Determination of the process by which the concentration ratios might be maintained inside cells at greatly differing values since NAD+ and NADP+ are essentially equivalent in their tendency to attract electrons.

Concept introduction:

The major electron donors required for reductive biosynthesis is nicotinamide adenine dinucleotide phosphate (NADPH). NADPH and NADP+ are similar to NADH and NAD+ respectively. The nicotinamide nucleotide-linked enzymes which act in catabolic direction use NAD+/ NADH, whereas those which act in anabolic reactions uses NADP+/NADPH.

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