Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Textbook Question
Chapter 11, Problem 13QP
A frameshift mutation is caused by a:
- a.
nucleotide substitution - b. three-base insertion
- c. premature stop codon
- d. one-base insertion
- e. two-base deletion
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Define the following terms: a. open reading frame b. degenerate coding system c. nonoverlapping coding sequence d. codon e. anticodon
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B. Insertion
C. Base-pair substitution
A mutation caused by a base deamination or a tautomerization is called a a. silent mutation b. transition mutation c. nonsense mutation d. missense mutation
Chapter 11 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 11.4 - Consumer products including bandages, cotton...Ch. 11.4 - Prob. 2EGCh. 11 - Prob. 1CSCh. 11 - Prob. 2CSCh. 11 - Prob. 3CSCh. 11 - Prob. 1QPCh. 11 - Achondroplasia is an autosomal dominant form of...Ch. 11 - Why is it almost impossible to directly measure...Ch. 11 - What are the factors that influence the mutation...Ch. 11 - Achondroplasia is a rare dominant autosomal defect...
Ch. 11 - Although it is well known that X-rays cause...Ch. 11 - Prob. 7QPCh. 11 - Bruce Ames and his colleagues have pointed out...Ch. 11 - Define and compare the following types of...Ch. 11 - If the coding region of a gene (the exons)...Ch. 11 - Two types of mutations discussed in this chapter...Ch. 11 - Prob. 12QPCh. 11 - A frameshift mutation is caused by a: a....Ch. 11 - In the gene-coding sequence shown here, which of...Ch. 11 - Prob. 15QPCh. 11 - Familial retinoblastoma, a rare autosomal dominant...Ch. 11 - Tay-Sachs disease is an autosomal recessive...Ch. 11 - Replication involves a period of time during which...Ch. 11 - Our bodies are not defenseless against mutagens...Ch. 11 - The cystic fibrosis gene encodes a chloride...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- In 1964, Nirenberg and Leder used the triplet binding assay to determine specific codon assignments. A complex of which of the following components was trapped in the nitrocellulose filter? (More than one may apply). A. Synthetic mRNA B. DNA C. Anti-codons D. Radioactive amino acids E. Large ribosomal subunits F. Small ribosomal subunitsarrow_forwardOriginal strand: G G G C T A G G G C C A A , Mutant strand: G G G G C T A G G G C C A A . What type of mutation? * A. Insertion B. Deletion C. Substitution D. Nonsense A base substitution that causes regular codon to change into another codon that codes for different amino acids is said to be; * A. missense mutations B. nonsense mutations C. silent mutations D. no correct response Mutagenic agents that can cause cancers are known specifically as; * A. mutagens B. carcinogens C. chemicals D. no correct response The process of copying a gene's DNA sequence into a sequence of RNA is called_____. * A. replication B. transcription C. translation D. PCR Which of the following…arrow_forwardWhich of the following mutations involve the loss of one or more nucleotides from a gene sequence? a.Base-pair substitution b.Insertion c.Deletionarrow_forward
- A missense mutation is a mutation in which: a. one nucleotide in a codon is changed, but the codon specifies the same amino acid b. a codon is deleted from a gene C. one nucleotide in a codon is changed, and the codon now specifies a different amino acid d. one nucleotide in a codon is changed, and the codon is now a stop codon rather than specifying an amino acid е. a truncated protein is produced by translationarrow_forwardWhich of the following mutations is NOT a point mutation? A. Missense mutation B. Insertion mutation C. Nonsense mutation D. Silent mutationarrow_forwardDefine the following terms: a. guanine nucleotide exchange factor (GEF) b. pretranslocation state c. posttranslocation state d. nascent polypeptide e. releasing factorsarrow_forward
- Complete each of the following statements by selecting from the bank of terms below. a. tRNA b. spontaneous c. repressible d. RNA processing e. mutagen f. SNRNA g. redundancy h. universal i. promoter j. elongation There are several three nucleotide codons that code for the same amino acid. This is known as (81). A specific three nucleotide codon for a fruit fly codes for the same amino acid as that same specific three nucleotide codon for a human. This means that the genetic code is (82). The three steps of transcription are initiation, (83), and termination. The (84) region on a chromosome is the sequence of nucleotides in DNA that indicates where the RNA polymerase complex should bind to initiate transcription. In a eukaryotic cell mRNA is modified in three ways. This is known as (85). The role of (86) is to combine with protein and then bind to introns to remove them and splice the RNA together. The role of (87) is to transport amino acids to the ribosome where the anticodon loop…arrow_forwardA small section of a gene for a protein has the following nucleotide sequence: CCT AAG GAT TCA CTT Which of the following mutations would cause a missense mutation in the sequence shown above? a. Replacement of first guanine base with cytosine base b. Replacement of first thymine base with cytosine base c. Replacement of second thymine base with adenine base d. Replacement of seond guanine base with adenine basearrow_forwardDefine the following terms: a. Okazaki fragment b. ter region c. tus protein d. transcription preinitiation complex e. ORCarrow_forward
- A small section of a gene for a protein has the following nucleotide sequence: CTA TCC CCT ACG TCA Which of the following mutations would cause a silent mutation in the sequence shown above? a. Replacement of first thymine base with adenine base b. Replacement of second thymine base with guanine base c. Replacement of first cytosine base with guanine base d. Replacement of second adenine base with thymine basearrow_forwardUse the sequences below to determine what type of mutation has occurred by comparing the normal sequence to the mutated sequence. Normal Gene Sequence: 3'- ATAGCTAAGCCCATGCGG-5' Mutated Gene Sequence 3'-ATAGCTAAGCCCAGGTGCGG-5' A. Deletion - Point Mutation B. Insertion - Chromosomal Mutation C. Deletion - Frameshift Mutation D. Substitution - Point Mutation E. Insertion - Frameshift Mutation F. Insertion - Point Mutationarrow_forwardA nonsense mutation Select one: a. results in a larger protein being produced from the mutated gene b. will lead to premature termination of translation c. is the same as a silent mutation d. will lead to the premature termination of transcriptionarrow_forward
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