Chapter 11, Problem 11.51P

Interpretation Introduction

Interpretation:

The three carbocation rearrangements in the synthesis of cholesterol from squalene as per Equation 11.38 are to be drawn using curved arrow notation.

Concept introduction:

Carbocations are prone to rearrangements. Generally, this rearrangement is driven by the formation of a more stable carbocation. There are three ways in which a carbocation rearrangement can occur – a $\text{1, 2-hydride}$ shift, a $\text{1, 2-methyl}$ shift, or a resonance rearrangement.