BIOLOGY
12th Edition
ISBN: 9781260169614
Author: Raven
Publisher: RENT MCG
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Chapter 10.7, Problem 2LO
Summary Introduction
To determine: The role associated with the p53 protein.
Introduction: Tumor is defined as the swelling part of the body in which cells are growing in an uncontrolled manner. The tumor will further become cancerous if it is not diagnosed.
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What must occur for TP53 to no longer function properly?
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Chapter 10 Solutions
BIOLOGY
Ch. 10.1 - Prob. 1LOCh. 10.2 - Prob. 1LOCh. 10.2 - Distinguish between homologues and sister...Ch. 10.2 - Prob. 3LOCh. 10.3 - Describe the eukaryotic cell cycle.Ch. 10.4 - Prob. 1LOCh. 10.4 - Prob. 2LOCh. 10.5 - Describe the phases of mitosis.Ch. 10.5 - Explain the importance of metaphase.Ch. 10.5 - Compare cytokinesis in plants and animals.
Ch. 10.6 - Prob. 1LOCh. 10.6 - Prob. 2LOCh. 10.7 - Prob. 1LOCh. 10.7 - Prob. 2LOCh. 10 - Binary fission in prokaryotes does not require the...Ch. 10 - Chromatin is composed of a. RNA and protein. b....Ch. 10 - What is a nucleosome? a. A region in the cells...Ch. 10 - What is the role of cohesin proteins in cell...Ch. 10 - The kinetochore is a structure that functions to...Ch. 10 - Separation of the sister chromatids occurs during...Ch. 10 - Why is cytokinesis an important part of cell...Ch. 10 - What steps in the cell cycle represent...Ch. 10 - Cyclin-dependent kinases (Cdks) are regulated by...Ch. 10 - Prob. 2ACh. 10 - Genetically, proto-oncogenes act in a dominant...Ch. 10 - The metaphase to anaphase transition involves a....Ch. 10 - The main difference between bacterial cell...Ch. 10 - In animal cells, cytokinesis is accomplished by a...Ch. 10 - Regulation of the cell cycle is very complex and...Ch. 10 - Review you knowledge of signaling pathways...Ch. 10 - Compare and contrast how mutations in cellular...
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- Define about Several types of cellular stress events bring about rapidincreases in the nuclear levels of activated p53 protein ?arrow_forwardCan you think of two ways in which the function of p53 can be disrupted?arrow_forwardThe p53 pathway is important for regulating the cell cycle. In a normal cell, there is a protein called mdm2 that can bind to p53 and deactivate it. A diseased individual has amutation in the gene that codes for mdm2, resulting in an mdm2 protein that is less able to bind to p53. Will this mutation increase, decrease, or cause no change in the rate of cell death? Explain.arrow_forward
- Mutations in p53 are commonly associated with malignant tumor formation. Do deleterious mutations in p53 usually lead to a loss of function or gain of function of the protein?arrow_forwardDescribe gene regulation by CpG islands.arrow_forwardExplain the regulation of Transcription-Factor Activity.arrow_forward
- p53 can trigger apoptosis if certain cell-cycle events fail. How does this regulatory outcome benefit a multicellular organism?arrow_forwardDescribe the ATM-p53 repair pathway in normal cells and cancerous cellsarrow_forwardDefine epigenetics and discuss the role of modifications to DNA and histone proteins in controlling gene expression and determining cell type.arrow_forward
- Describe epigenetic alterations .arrow_forwardThe p53 protein regulates the expression of BAX and Bcl2 to keep division at normal rate. Explain how is this achieved?arrow_forwardActivation of p53 during cellular stress will generally Select one: o a. Increase transcription of cyclin-dependent kinase inhibitors and decrease the likelihood of apoptosis. o b. Decrease transcription of cyclin-dependent kinase inhibitors and decrease the likelihood of apoptosis. o c. Increase transcription of cyclin-dependent kinase inhibitors and increase the likelihood of apoptosis. o d. Decrease transcription of cyclin-dependent kinase inhibitors and increase the likelihood of apoptosis.arrow_forward
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