Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 10.3, Problem 1CC
Do the ends of protein-encoding genes have a poly T region that provides a template for the synthesis of a poly A tail in mRNA? Explain.
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The mRNA formed from the repeating tetranucleotide UUACincorporates only three amino acids, but the use of UAUC incorporates four amino acids. Why?
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How many amino acids would the encoded protein be? Assume that the N- terminal Met encoded by the AUG start codon, is NOT cleaved from the protein?
Explain why the translation of a given mRNA can be inhibited by a segment of its complementary sequence, a so-called antisense RNA.
Chapter 10 Solutions
Principles of Biology
Ch. 10.1 - What is the direction of flow of genetic...Ch. 10.1 - Prob. 1TYKCh. 10.1 - Prob. 2TYKCh. 10.1 - Prob. 3TYKCh. 10.2 - How would removing a terminator from a gene affect...Ch. 10.2 - Prob. 1BCCh. 10.2 - Prob. 1TYKCh. 10.2 - Prob. 2TYKCh. 10.3 - Do the ends of protein-encoding genes have a poly...Ch. 10.3 - The splicing of pre-mRNA in eukaryotes involves...
Ch. 10.3 - Prob. 2TYKCh. 10.4 - Prob. 1CCCh. 10.4 - Prob. 2CCCh. 10.4 - Prob. 1TYKCh. 10.4 - Prob. 2TYKCh. 10.5 - Prob. 1CCCh. 10.5 - Prob. 1BCCh. 10.5 - Based on the gene sequences shown here, pick two...Ch. 10.5 - Prob. 1TYKCh. 10.5 - Prob. 2TYKCh. 10.5 - Prob. 3TYKCh. 10.6 - Prob. 1CCCh. 10.6 - Prob. 1TYKCh. 10.6 - Prob. 2TYKCh. 10 - Which of the following best represents the central...Ch. 10 - Prob. 2TYCh. 10 - Prob. 3TYCh. 10 - Prob. 4TYCh. 10 - Prob. 5TYCh. 10 - Prob. 6TYCh. 10 - The legion of a tRNA that is complementary to a...Ch. 10 - Prob. 8TYCh. 10 - Prob. 9TYCh. 10 - Prob. 10TYCh. 10 - Lets suppose a gene mutation changed the sixth...Ch. 10 - What is the function of an aminoacyl-tRNA...Ch. 10 - A principle of biology is that the genetic...Ch. 10 - Prob. 1CBQCh. 10 - Prob. 2CBQ
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- One of the codons in mRNA that specifies the amino acid phenylalanine is UUC. What is the anticodon on the tRNA that carries phenylalanine?arrow_forwardThe primary protein structure is shown in Figure 9-3(a).Where in the mRNA (near the 5′or 3′end) would a mutation in R2 be encoded?arrow_forwardWhat is the sequence of bases in the template strand of DNA that codes for the mRNA in Problem?arrow_forward
- A eukaryotic cell carrying out transcription and RNA processing is incubated with 32P-labeled ATP. Where will the radioactive isotope appear in mature mRNA if the ATP is labeled at the (a) α position, (b) β position, and (c) γ position?arrow_forwardHow does the poly(A) tail affect mRNA stability?arrow_forwardSuppose the codon sequence GUGCAAUUCGAGGCC has a single base pair mutation to GUGCAAUUCAAGGCC. If the old protein sequence was Val-Gln-Phe-Glu-Ala, what will be the new sequence encoded by the mutant gene? ____________________________.arrow_forward
- Given the following mRNA sequence: 5-AUCCCGUAUGCCCGGGAGCUAGCCCAGC-3 a) Label the first condon, the stop codon, the untranslated regions and predict the amino acid sequence of the polypeptidarrow_forwardHere is a eukaryotic gene. The numbers given are base pairs of exon and intron. How long in bases will the pre mRNA transcript be? Explain briefly. What is the maximum number of amino acids that could make up the protein product from the final mRNA? Explain briefly.arrow_forwardAlthough Ribosome binding site sequence vary considerably in different genes, they include examples like GAGGGG that could serve as code for Glu-Gly. Does this imply that the amino acid sequence Glu-Gly can never occur in a protein, lest the two mRNA codons be read as a RBS sequence? Explainarrow_forward
- What mRNA is most obviously essential in coding proteins, list and describe two classes of non-coding RNAs that are required for translation?arrow_forwardA. What amino acid sequence is encoded by the codon sequence AUAAUGGUAACGGUU? B. Suppose the codon sequence AGACACUCUAUUAAA has a single base pair mutation to AGACACUCUUUUAAA. If the old protein sequence was Arg-His-Ser-Ile-Lys, what will be the new sequence encoded by the mutant gene?arrow_forwardHow would a mutation in the poly(A)-binding protein gene affect translation? How would an electron micrograph of polyribosomes from such a mutant differ from the normal pattern?arrow_forward
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