Interpretation:
The pH of the resultant HCl solution needs to be calculated.
Concept introduction:
When a solution is diluted, the molarity of solution changes according to the dilution law which is mathematically represented as follows:
Here,
A strong acid dissociates completely into hydrogen ion and conjugate base as follows:
Thus, the concentration of hydrogen ion will be same as that of acid.
From the hydrogen ion concentration, the pH of the solution can be calculated as follows:
Here,
Trending nowThis is a popular solution!
Chapter 1 Solutions
BIOCHEMISTRY (LOOSELEAF)-W/ACCESS
- Isotonicity. Show your complete solution. 1. A hospital pharmacist fills a medication order calling for an intravenous fluid of dextrose 5% in a 0.9% sodium chloride injection and 40 mEq of potassium chloride in a total volume of 1000 mL. The intravenous infusion is administered through an IV set that delivers 15 drops per milliliter. The infusion has been running at a rate of 12 drops per minute for 15 hours. During the 15-hour period: (a) How many mEq of KCl have been administered? (b) How many grams of KCl have been administered? (c) How many millimoles of KCl have been administered? (d) What is the total osmolarity of the intravenous fluid? Express the answer in millimoles (rounded to the nearest whole number) per 1000mL.arrow_forwardPart I. For each of the following four questions: calculate and describe how the requested solution would be made. Please show all of your calculations. In all cases the diluent or solvent will be water. Also, assume the smallest volume you can accurately pipette is 1ul. (CaClh: Molecular weight = 111.0 - NaCl: Molecular weight= 58.44) 1. From a 3M CaCh stock solution, you need to make 600 ml of 9 mM CaClh. Indicate how you would make it. 2. You have a 20ul sample of DNA that you want to run in a gel. You are given 5X track dye; how much track dye do you add to your sample so that the track dye concentration in the sample is 1X? 3. You need to make 6 liters of 20% NaCl solution. Indicate how you wvould make it firom powdered NACI.arrow_forwardHelp please. MD ordered morphine SO4 gr 2/5 and the pharmacist has a stock solution of gr 1/8 per milliliter of morphine SO4. How many milliliters of the stock solution is required to fill the Rx?arrow_forward
- Benzalkonium chloride (E=0.16) 1.5g qs 100 ml Distilled water 0.9% Nacl solution ad Make isotonic solution Questions: 1. How many ml of distilled water must be added to make the Benzalkonium chloride preparation isotonic? 2. How many ml of 0.9% NaCl must be added to make a 100ml solution?arrow_forwardBe sure to answer all parts. Tris [tris(hydroxymethyl)aminomethane] is a common buffer for studying biological systems. (K, = 5.01 x 109 and pk, 8.3) %3D %3D (a) Calculate the pH of the Tris buffer after mixing 10.5 mL of 0.20 M HCI solution with 25.0 mL of 0.10 M Tris. 7.06 (b) This buffer was used to study an enzyme-catalyzed reaction. As a result of the reaction, 0.00020 mol of H* was produced. What is the pH of the buffer at the end of the reaction? (c) What would be the final pH if no buffer were present?arrow_forwardV-A. Which of the following amino acids will elute first in a cation-exchange column using a buffer at pH 7? 1. Asp or Lys 2. Arg or Met 3. Gly or Val 4. Ser or Alaarrow_forward
- 1- Using the pH 12 of the buffer and the pKa = 12.32. What is the molar ratio of A- to HA. 2- What is the molar amount of A- and HA needed to prepare a 0.2 M buffer? 3- How many grams of A- and HA are needed to prepare 40 mal of the buffer? The molar mass of HA is 142g/mol The molar mass for A- is 380.1g/molarrow_forwardpH of solution 14.00 12.00 10.00 8.00 6.00 First 4.00 equivalence point 2.00 0 First midpoint Second equivalence point Third midpoint pH = pKa=12.32 Third equivalence point HPO4(aq) + OH(aq) PO4(aq) + H2O(1) Second midpoint pH = pKa = 7.21 H2PO4 (aq) + OH(aq) HPO42 (aq) + H2O(1) Using the Henderson- Hasselback equation, show how to create 2L of a 0.1 M KPhos pH 7.5 buffer using K2HPO4 and KH2PO4. The chart to the left should help you understand what pKa to start with. Show your work. pH = pKa = 2.16 H3PO4(aq) + OH(aq) H2PO4(aq) + H2O(l) 25.0 50.0 75.0 100.0 Volume of NaOH added (mL)arrow_forwardPenicillin G potassium 5000 units Isotonic Sodium Chloride Solution ad 15 mL Sig. Nose drop Using soluble penicillin tablets, each containing 100,000 units of crystalline penicillin G potassium, explain how you would obtain penicillin G potassium needed in compounding the prescription.arrow_forward
- An appropriate biochemical buffer should have charges in both its conjugate acid and conjugate base form. This avoids the presence of a neutral form of the buffer that might be able slowly leak into cells. Does unmodified dimethylpiperazine meet this criterion when buffering at pH 8? O Yes No What about buffering at pH 4? D Yes Noarrow_forwardParaphrasing Tool . medicinal meet Mniversity of Nizwa pKa of flurazepam is 8.71. Ifthe pH of the stomach is 3.5 and that of intestine is 6.0 then oral flurazepam will be t of Flurazepam Select one: a. ionized in the stomach and neutral in the intestine O b. neutral in the stomach and ionized in the intestine O c. ionized in both the stomach and the intestine O d. neutral in both the stomach and the intestine Which of the following molecules is neutral?arrow_forwardO b. False How much of ethanol you need to prepare 25% (v/v) ethanol solution Select one: O a. 75 ml O b. 75 g O c. 25 ml Od. 25 g The function of buffers is to Select one: ea Resist changes in pH. Ob. Fx the pH of solution Oc Resist changes in confugate acid .concentration d. Resist changes in weakacid .concentrationarrow_forward
- BiochemistryBiochemistryISBN:9781319114671Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.Publisher:W. H. FreemanLehninger Principles of BiochemistryBiochemistryISBN:9781464126116Author:David L. Nelson, Michael M. CoxPublisher:W. H. FreemanFundamentals of Biochemistry: Life at the Molecul...BiochemistryISBN:9781118918401Author:Donald Voet, Judith G. Voet, Charlotte W. PrattPublisher:WILEY
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage LearningBiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage LearningFundamentals of General, Organic, and Biological ...BiochemistryISBN:9780134015187Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. PetersonPublisher:PEARSON