You have an E.coli strain in which the lac operon is not expressed when glucose is absent and lacto is present. You have already conducted tests with partial diploids to rule out lacl, lacO, lacZ, lacY ar lacA as the culprits, so you know that something must be wrong with the positive regulation syster Which of the following mutations could be causing this mutant phenotype? cya- where glucose cannot bind adenylate cyclase cap- where CAMP cannot bind to CAP cap- where CAP cannot bind to the CAP binding site O Mutation in the CAP binding site that prevents CAP from binding O cya- where adenylate cyclase cannot turn ATP into CAMP

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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select all the mutations that could apply

You have an E.coli strain in which the lac operon is not expressed when glucose is absent and lactose
is present. You have already conducted tests with partial diploids to rule out lacl, lacO, lacZ, lacY and
lacA as the culprits, so you know that something must be wrong with the positive regulation system.
Which of the following mutations could be causing this mutant phenotype?
O cya- where glucose cannot bind adenylate cyclase
O cap- where CAMP cannot bind to CAP
O cap- where CAP cannot bind to the CAP binding site
Mutation in the CAP binding site that prevents CAP from binding
O cya- where adenylate cyclase cannot turn ATP into CAMP
Transcribed Image Text:You have an E.coli strain in which the lac operon is not expressed when glucose is absent and lactose is present. You have already conducted tests with partial diploids to rule out lacl, lacO, lacZ, lacY and lacA as the culprits, so you know that something must be wrong with the positive regulation system. Which of the following mutations could be causing this mutant phenotype? O cya- where glucose cannot bind adenylate cyclase O cap- where CAMP cannot bind to CAP O cap- where CAP cannot bind to the CAP binding site Mutation in the CAP binding site that prevents CAP from binding O cya- where adenylate cyclase cannot turn ATP into CAMP
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