You are studying the M-cyclin. You treat mitotic cells with an inhibitor of the proteasome and find that M-cyclin is no longer degraded and that this prolongs mitosis. You also find that in the presence of the inhibitor, M-cyclin is now running slower/larger in a Western than you have previously observed. In 1-2 sentences, explain why this might be happening.

Q: 1) One cell-signaling pathway implicated in the regulation of cell division is the mTOR/Akt pathway.…

A: mTOR/Akt pathway involved in cell division.

Q: Can you please help me by drawing a serie of schematic figures that demonstrates the information in…

A: Proteins undergo post-translational modifications to increase their functional diversity. The…

Q: Describe what happens to the G1 cell cycle check point of a skin cell that is stimulated to divide…

A: Transformation of cells from one phase of the cell cycle to another is controlled by some external…

Q: A. Cyclin Expression Cycle 1. What are the two factors involve in the illustration Cyclin Expression…

A: INTRODUCTION : Cyclins - Cyclins are classified as a group of proteins which are similar or related…

Q: Which of the following statements is a lie? Select one: a. If damaged DNA is detected during the…

A: A cell cycle is a sequence of events that occur in a cell as it divides and expands. After that, the…

Q: There are several main model systems through which the first set of major breakthroughs in the…

A: The initial advances in our comprehension of cell cycle regulation are the topic of the question.…

Q: If  I extract a cell culture with 100 cells that just entered g1.  I needs to extract the MOST…

A: Introduction: Cell cycle is the process by which a cell replicates i.e. makes copies of itself or…

Q: When a motile cell wants to change the direction of the movement; it remodels the actin under the…

A: The cytoskeleton proteins in the cells are responsible for different functions in the cells. The…

Q: There are several regulation mechanisms for the progression of a cell through the cell cycle and for…

A: Cyclin - dependent kinases (Cdks) and cyclins are the proteins, that drive  and regulate cell cycle.…

Q: Is the DNA in these cells identical or different? Why or why not? 200mb ONA IS is different because…

A: Cell division is the process through which a parent cell divides into two daughter cells. The two…

Q: You have isolated a strain of mutant yeast cells that divide normally at 25 degrees Celsius but…

A: Cell division is a normal process that occurs in all living organisms to produce new cells to…

Q: Predict the effects of the following mutations on the ability of a cell to undergo apoptosis:a.…

A: KEY WORDS :- Mutations - Structure or the process of gene is changed or have any effect which can…

Q: A mutated form of protein p5x is found in patients with squamous cell carcinoma. In vitro studies…

A: A gene that produces a protein that is essential for regulating cell division and death and is…

Q: Imagine that you are working with DNA sequences of membrane proteins) and have the technology to…

A: Protein synthesis can be mediated by membrane free ribosome or membrane bound ribosome. Actually the…

Q: You are studying cancer progression in mice. Your results show the following pathway in which two…

A: From the given data the observations made are: The experiment is conducted in a nutrient-enriched…

Q: A cultured mouse cell line has a mutation in a gene encoding a ribosomal protein. The mutant protein…

A: Chaperones are a kind of protein with similar properties that aid in protein folding. These proteins…

Q: Protein P, normally stimulates apoptosis or cell death when activated. Consider a cell with a…

A: The construction of this question gives us an  information about the nature of protein P, P when…

Q: Drug A323 inhibits the activity of the cyclin-dependent kinase (CDK) - G1 cyclin complex. Consider…

A: Answer 1:- Cyclin Dependent Kinases perforn an important role of controlling cell division and tune…

Q: The protein Tau promotes formation of axonal microtubules, stabilizes them, and drives neurite…

A: Microtubules are hollow , cylindrical and consists of 13 protofilaments. It is present in all…

Q: kinases/phosphatases OR proteasomes ensures proper rates of cell division.

A:

Q: enzyme (Tyr 15 of phorylated, the en- -ylation state of any lows replication. The role of Cdk…

A: The cell cycle is highly regulated by different regulatory proteins that includes the cdc2 and…

Q: Which of the following events destabilize microtubules at the kinetochore? O Preventing Ndc80…

A: A chromosome has two microtubules arising from its kinetochore. In the anaphase, the kinetochore…

Q: The destruction of the various cyclins is commonly used to inactivate the Cdk/cyclin complexes. Why…

A: Cancer or tumor growth occurs when the cell cycle regulation mechanisms fail to stop the division of…

Q: Explain how cyclin D-CDK 4/6, Rb and E2F work in the presence of growth factor to get the cell…

A: Cyclin CDK 4/6 are the cyclin-dependent kinases that help in moving the cell from the G1 phase to…

Q: In attempting to design a drug that will impede cell cycle progression in ovarian cancers cells. you…

A: The answer is none of these.The cell cycle is a tightly regulated process that controls the growth…

Q: What are the three protein families that regulate the cell cycle?

A: The cell cycle control framework depends on consistently actuated protein kinases.  At the core of…

Q: Hoechst 33258 is a chemical dye that binds specifically to DNA in live cells, and when excited by UV…

A: A cell is a mass of cytoplasm that is bound by a cell membrane. Generally smaller in size, cells are…

Q: You are studying three proteins that you think are important Yor progression through the cell cycle.…

A: The proteins involved in cell cycle progression are cyclin dependant kinases (cdks) and cyclins.…

Q: Cells of random sizes (some very small) are formed after cell division Normal sized cells are formed…

A: This ftsz protein that stands for filamentous temperature-sensitive protein Z plays a very important…

Q: Anaphase B involves the separation of spindle poles. What forces have been proposed to drive this…

A: Anaphase is the third stage, followed by metaphase that is characterized by the seperation of…

Q: A cell in M phase with chromosomes not properly connected to the spindle apparatus should delay the…

A: Four different cyclins act to complete the cell cycle. The cyclins are cyclin D, cyclin E cyclin A,…

Q: You are studying Protein X which plays a role in promoting the G1/S phase transition in eukaryotic…

A: The G1 phase of the cell cycle is that phase that occurs after the cell division and just before the…

Q: This phosphatase removes an inhibitory phosphotyrosine phosphate from serine protein kinase,…

A: For cell proliferation and cell growth, cell division occurs. A cell undergoes a cell cycle before…

Q: could you explain a bit more what this sentences mean: The information displayed demonstrates a…

A: Dentate gyrus is an important region in the hippocampal formation of the brain. This portion is…

Q: Explain the concept of loss of heterozygosity (LOH). Why do most cancer cells exhibit LOH of one or…

A: The loss or inactivation of a normal allele in a normal or somatic cell is a requirement for cancer…

Q: C. the cell immediately enters mitosis

A: The cell cycle is the series of events that occur in a cell leading to its division and duplication.…

Q: Vinblastine is a standard chemotherapeutic drug used to treat cancer. Because it interferes with the…

A: There are a few important points : Abnormal proliferation of cells without differentiation and…

Q: When regulating the cell cycle of eukaryotic cells, a critical protein we discussed was cyclin.…

A: Cyclins are a type of protein that do not have any enzymatic activity on their own but cyclins bind…

Q: Which of the following statements is a lie? Select one: a. The p21 is a multi-functional protein…

A: The cell cycle can be influenced by either the initiation or inhibition of the cell division. It is…

Q: A. Name the two proteins that induce a negative feedback in this pathway and explain why both…

A: Since, you have posted multiple questions we will solve the first question for you. If you want any…

Q: Cancer cells typically lose cell cycle entry control. Explain how the following mutations, which are…

A: Mutations are changes or alterations that occur in the DNA. Mutagens are the agents that are…

Q: A greater number of protocadherin genes ____.

A: Protocadherins are a family of cell adhesion molecules, and they play a crucial role in neuronal…

Q: What do you think would happen to the cell cycle of cells that contain a point mutation in the S-…

A: Cyclin and cyclin dependent kinase play a very important role in the progression of cell cycle. Cell…

Q: Notch signaling orchestrates transition from G1 to S phase of cell cycle by multiple other…

A: Notch signaling is a profoundly conserved cell communication pathway that plays an essential part in…