Write the structure of each nucleotide-linked sugar in the pathway shown in Figure UDP-N-Acetylglucosamine Еpimerase UDP-N-Acetylgalactosamine ATP UDP Kinase ADP- N-Acetylmannosamine-6-phosphate -Phosphoenolpyruvate 3-Carbon addition N-Acetylneuraminic acid 9-phosphate -H20 Phosphatase Pi N-Acetylneuraminic acid (sialic acid)
Write the structure of each nucleotide-linked sugar in the pathway shown in Figure UDP-N-Acetylglucosamine Еpimerase UDP-N-Acetylgalactosamine ATP UDP Kinase ADP- N-Acetylmannosamine-6-phosphate -Phosphoenolpyruvate 3-Carbon addition N-Acetylneuraminic acid 9-phosphate -H20 Phosphatase Pi N-Acetylneuraminic acid (sialic acid)
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:Write the structure of each nucleotide-linked sugar in the pathway
shown in Figure
Transcribed Image Text:UDP-N-Acetylglucosamine
Еpimerase
UDP-N-Acetylgalactosamine
ATP
UDP
Kinase
ADP-
N-Acetylmannosamine-6-phosphate
-Phosphoenolpyruvate
3-Carbon addition
N-Acetylneuraminic acid 9-phosphate
-H20
Phosphatase
Pi
N-Acetylneuraminic acid (sialic acid)
Expert Solution
Step 1
The nucleotide sugars are the activated forms of monosaccharides and they act as glycosyl donors in the glycosylation reactions which are catalyzed by glycosyltransferases. There are ten different types of nucleotide sugars that can act as glycosyl donors such as UDP, uridine diphosphate, GDP, guanine diphosphate, CDP, cytosine diphosphate, CMP, cytosine monophosphate, etc.
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