[word1] is the number of individuals with a genotype who manifest a distinct phenotype? 1-Epistasis 2-Expressivity 3-Variance 4-Penetrance

Duchenne’s muscular dystrophy (DMD) is an X-linked disease that causes progressive muscle weakness and is often fatal. “XD” represents the wild type allele, and “Xd,” the mutant allele. Jonah is XDXd Y and his brother Pete is Xd Y. Jonah and Pete BOTH have DMD of equal severity and phenotypes. You might have thought Jonah’s DMD would be less severe given his genotype. To better understand the situation, you investigate Jonah’s Xist chromosome region in his defective muscle cells. Which of the following is consistent with his phenotype? (Select all that apply.) The Xd-containing chromosome is inactive in defective muscle cells. The XD-containing chromosome has a methylated Xist promoter. The XD-containing chromosome has an unmethylated Xist promoter. The Xd-containing chromosome is active in defective muscle cells.

For each of the following genotypes state whether you have a homozygous or heterozygous for each trait (you may need to use 2 terms for one genotype). AaGG Rrgg TTGg

determine if the possible alleles are complete dominate, incomplete dominance, or codominance.

Jenny's maternal uncle (her mother's brother) is affected with a rare x-linked disease, but no one else in the family is.  What is the percent chance that Jenny is a carrier of this disease? Enter a whole number between 0 and 100.  For example, if you enter 33, it means you think there is 33% chance that Jenny is carrier.

To play Jeopardy, the answer is given. You must supply the question. Choose the best question for the following answer: Mutant allele causing malfunction of the wild-type allele, giving rise to a dominant phenotype. What is codominance? What is incomplete dominance? O What is dominant negative? O What is haploinsufficiency?

The dominant form of Enzyme 1 makes blue pigment. However, individuals with this allele only have blue eyes if they also have a functional copy of the protein that produces the substrate for Enzyme 1. what is this an example of      Traditional mendelian dominance      Sex-linked traits     Gene Dosage     Epistasis     Codominance

X-linked Recessive Inheritance A gene is described as X-linked when it occurs on the X chromosome and not the Y. Our convention is to indicate X-linkage by attaching the appropriate gene symbol as a superscript on the letter X. Commonly, the wild-type (+) allele is indicated with only a "+" to avoid having to type a superscript on a superscript. For example, a female that is heterozygous and carrying a recessive mutant allele is indicated as X+Xm. Note the convenience of the shorthand + for m+ in this situation. A mutant male has the genotype XmY. When working with X-linked inheritance, always include the X and Y chromosomes in the descriptions of genotypes, and include the sex (male or female) in the descriptions of the phenotypes (e.g., mutant male, wild-type female, etc.). Here are the genotypes and associated phenotypes for X-linked recessive inheritance: X+X+ Wild-type female X+Xm Wild-type female xmxm Mutant female X+Y xmy Wild-type male Mutant male