QUESTION 5 For the following pedigree, assume that the mode of inheritance is X-linked dominant, and that the trait has full penetrance and expressivity. I III IV 2 3 4 1 2 5 6 ДО 1 2 3 4 5 6 7 8 9 1234 7 8 OC 10 11 12 13 14 15 On O 5678

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Chapter9: Patterns Of Inheritance
Section: Chapter Questions
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QUESTION 5
For the following pedigree, assume that the mode of inheritance is X-linked dominant, and that the trait has full penetrance and
expressivity.
I
11
IV
1
2
3 4
1 2
5
6 7 8
HOOD
OD
FO
1 2 3 4 5 6 7 8 9
1 2 3 4
OOD OC
10 11 12 13 14 15
☐☐
5678
Transcribed Image Text:QUESTION 5 For the following pedigree, assume that the mode of inheritance is X-linked dominant, and that the trait has full penetrance and expressivity. I 11 IV 1 2 3 4 1 2 5 6 7 8 HOOD OD FO 1 2 3 4 5 6 7 8 9 1 2 3 4 OOD OC 10 11 12 13 14 15 ☐☐ 5678
Using XA (XA) for the dominant allele and Xa (Xa) for the recessive allele, assign genotypes for the following individuals (if it is not
possible to figure out the second allele of a genotype, indicate that with an underscore). Remember that males are hemizygous for
genes on the X (i.e. they have a Y chromosome).
1-1:
1-2:
11-8:
11-9:
If individuals Il-1 and II-2 have another child, what is the probability that they will have an affected daughter?
Transcribed Image Text:Using XA (XA) for the dominant allele and Xa (Xa) for the recessive allele, assign genotypes for the following individuals (if it is not possible to figure out the second allele of a genotype, indicate that with an underscore). Remember that males are hemizygous for genes on the X (i.e. they have a Y chromosome). 1-1: 1-2: 11-8: 11-9: If individuals Il-1 and II-2 have another child, what is the probability that they will have an affected daughter?
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